Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:APOC3_HUMAN
Description:apolipoprotein C-III [Source:HGNC Symbol;Acc:610]
Location:chr11 q23.3
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T94PEVRPtSAVHPRD
S95EVRPTsAVHPRD
S82VKDKFsEFWDLHPRD

Dephosphorylation site
APOC3_HUMAN do not have dephosphorylation site.

Mutation site
APOC3_HUMAN do not have mutation site.

Differential expressed protein
APOC3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
APOC3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
USF2_HUMANAPOC3_HUMANTF -> target geneTRANSFAC
USF1_HUMANAPOC3_HUMANTF -> target geneTRANSFAC
COT2_HUMANAPOC3_HUMANTF -> target geneTRANSFAC
COT1_HUMANAPOC3_HUMANTF -> target geneTRANSFAC
HNF4A_HUMANAPOC3_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
APOC3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0010989negative regulation of low-density lipoprotein parIMPbiological_process
GO:0006642triglyceride mobilizationIEAbiological_process
GO:0034382chylomicron remnant clearanceIDAbiological_process
GO:0034363intermediate-density lipoprotein particleIDAcellular_component
GO:0030234enzyme regulator activityIDAmolecular_function
GO:0032489regulation of Cdc42 protein signal transductionIDAbiological_process
GO:0042493response to drugIEAbiological_process
GO:0019433triglyceride catabolic processIEAbiological_process
GO:0008203cholesterol metabolic processIEAbiological_process
GO:0006641triglyceride metabolic processIEAbiological_process
GO:0010897negative regulation of triglyceride catabolic procIDAbiological_process
GO:0006629lipid metabolic processTASbiological_process
GO:0010916negative regulation of very-low-density lipoproteiIDAbiological_process
GO:0010903negative regulation of very-low-density lipoproteiICbiological_process
GO:0008289lipid bindingIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0034379very-low-density lipoprotein particle assemblyTASbiological_process
GO:0042632cholesterol homeostasisIMPbiological_process
GO:0051005negative regulation of lipoprotein lipase activityIDAbiological_process
GO:0042157lipoprotein metabolic processIEAbiological_process
GO:0060621negative regulation of cholesterol importIMPbiological_process
GO:0048261negative regulation of receptor-mediated endocytosIDAbiological_process
GO:0042953lipoprotein transportIEAbiological_process
GO:0042627chylomicronIDAcellular_component
GO:0034366spherical high-density lipoprotein particleIDAcellular_component
GO:0005615extracellular spaceIEAcellular_component
GO:0055102lipase inhibitor activityIDAmolecular_function
GO:0050995negative regulation of lipid catabolic processIDAbiological_process
GO:0034361very-low-density lipoprotein particleIDAcellular_component
GO:0010987negative regulation of high-density lipoprotein paIMPbiological_process
GO:0033344cholesterol effluxIDAbiological_process
GO:0045717negative regulation of fatty acid biosynthetic proIDAbiological_process
GO:0034375high-density lipoprotein particle remodelingIMPbiological_process
GO:0006869lipid transportIEAbiological_process
GO:0045833negative regulation of lipid metabolic processIDAbiological_process
GO:0070653high-density lipoprotein particle receptor bindingIPImolecular_function
GO:0007186G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0033700phospholipid effluxIDAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0043691reverse cholesterol transportICbiological_process
GO:0005543phospholipid bindingIDAmolecular_function
GO:0007584response to nutrientIEAbiological_process
GO:0070328triglyceride homeostasisIMPbiological_process
GO:0006641triglyceride metabolic processIMPbiological_process
GO:0015485cholesterol bindingICmolecular_function
GO:0043434response to peptide hormone stimulusIEAbiological_process