Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AOFB_HUMAN
Description:monoamine oxidase B [Source:HGNC Symbol;Acc:6834]
Location:chrX p11.3
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y44VGGRTyTLRNQAmino_oxidasePhosphoSitePlus
Y383LEPVHyEEKNWAmino_oxidasePhosphoSitePlus
Y337KPEGNyAAIMGAmino_oxidasePhosphoSitePlus
Y60DLGGSyVGPTQAmino_oxidasePhosphoSitePlus
T43RVGGRtYTLRNAmino_oxidasePhosphoSitePlus
Y53NQKVKyVDLGGAmino_oxidasePhosphoSitePlus

Dephosphorylation site
AOFB_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000367309F274ICOSMICOvarian Cancer21720365
ENSP00000367309E359KBIOMARTBreast Cancer21930507, 21930502
ENSP00000367309R208KCOSMICSkin Cancer21984974
ENSP00000367309P266LCOSMICSkin Cancer21984974
ENSP00000367309T356ICOSMICSkin Cancer21984974

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000367309Breast CancerNormal vs. CancertissueDown0.6920739354
ENSP00000367309Breast CancerNormal vs. CancertissueDown0.6920739354

Hyperphosphorylation site
AOFB_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EGR1_HUMANAOFB_HUMANTF -> target geneTRANSFAC
SP3_HUMANAOFB_HUMANTF -> target geneTRANSFAC
SP1_HUMANAOFB_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
AOFB_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008131primary amine oxidase activityTASmolecular_function
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0016491oxidoreductase activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0048545response to steroid hormone stimulusIEAbiological_process
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0010269response to selenium ionIEAbiological_process
GO:0010044response to aluminum ionIEAbiological_process
GO:0050660flavin adenine dinucleotide bindingIEAmolecular_function
GO:0042493response to drugIEAbiological_process
GO:0006805xenobiotic metabolic processTASbiological_process
GO:0045964positive regulation of dopamine metabolic processIEAbiological_process
GO:0014063negative regulation of serotonin secretionIEAbiological_process
GO:0005740mitochondrial envelopeTAScellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0051412response to corticosterone stimulusIEAbiological_process
GO:0005743mitochondrial inner membraneIEAcellular_component
GO:0009636response to toxinIEAbiological_process
GO:0005741mitochondrial outer membraneTAScellular_component
GO:0005739mitochondrionIEAcellular_component
GO:0055114oxidation-reduction processIEAbiological_process
GO:0009055electron carrier activityTASmolecular_function
GO:0045471response to ethanolIEAbiological_process


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