| UniProt/SwissProt ID: | AKIP_HUMAN |
| Description: | aurora kinase A interacting protein 1 [Source:HGNC Symbol;Acc:24114] |
| Location: | chr1 p36.33 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S70 | VPRKMsVSPLE | PhosphoSitePlus | |
| Dephosphorylation site |
| AKIP_HUMAN do not have dephosphorylation site. |
| Mutation site |
| AKIP_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000368130 | Testicular Cancer | Normal vs. Cancer | cell line | Down | 18489135 | |
| Hyperphosphorylation site |
| AKIP_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | AKIP_HUMAN | kinase -> substrate | RegPhos |
| CSK21_HUMAN | AKIP_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| AKIP_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0045862 | positive regulation of proteolysis | IDA | biological_process |
| GO:0005739 | mitochondrion | IEA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0045839 | negative regulation of mitosis | NAS | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005739 | mitochondrion | IDA | cellular_component |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | cellular_component |