| UniProt/SwissProt ID: | AKA10_HUMAN |
| Description: | A kinase (PRKA) anchor protein 10 [Source:HGNC Symbol;Acc:368] |
| Location: | chr17 p11.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S52 | SISVHsPQKST | PhosphoSitePlus; HPRD | |
| S24 | PGPAMsFFRRK | PhosphoSitePlus | |
| S56 | HSPQKsTKNHA | PhosphoSitePlus | |
| T229 | DLNNRtNSTQN | RGS | PhosphoSitePlus |
| S269 | TQESSsTLTVA | RGS | PhosphoSitePlus |
| S187 | LAEPVsPSKKH | RGS | PhosphoSitePlus |
| Y113 | RSCLDyQTQET | PhosphoSitePlus | |
| S187 | LAEPVsPSKKH | HPRD | |
| T448 | FSLQAtHPLGF | RGS | PhosphoSitePlus |
| S267 | METQEsSSTLT | RGS | PhosphoSitePlus |
| T90 | SSRTAtLKKQP | PhosphoSitePlus | |
| Y442 | ILYDKyFSLQA | RGS | PhosphoSitePlus |
| S281 | RNSPAsPLKEL | RGS | PhosphoSitePlus |
| S281 | RNSPAsPLKEL | HPRD; phosphoELM | |
| S47 | KSIKAsISVHS | PhosphoSitePlus | |
| T272 | SSSTLtVASRN | RGS | PhosphoSitePlus |
| S96 | LKKQPsHMEAA | PhosphoSitePlus | |
| Dephosphorylation site |
| AKA10_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000225737 | C366R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000225737 | *663G | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| AKA10_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| AKA10_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCT_HUMAN | AKA10_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| AKA10_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0038032 | termination of G-protein coupled receptor signalin | IEA | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0005739 | mitochondrion | IEA | cellular_component |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0008104 | protein localization | IEA | biological_process |