| UniProt/SwissProt ID: | AGRP_HUMAN |
| Description: | agouti related protein homolog (mouse) [Source:HGNC Symbol;Acc:330] |
| Location: | chr16 q22.1 |
| Node attribute: | ligand; PPI(target) |
| Phosphorylation site |
| AGRP_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| AGRP_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000290953 | *133K | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| AGRP_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| AGRP_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| AGRP_HUMAN | MC4R_HUMAN | ligand -> receptor | HPMR |
| AGRP_HUMAN | MC3R_HUMAN | ligand -> receptor | HPMR |
| AAKG2_HUMAN | AGRP_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04920 | Adipocytokine signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007218 | neuropeptide signaling pathway | IDA | biological_process |
| GO:0060259 | regulation of feeding behavior | IDA | biological_process |
| GO:0005184 | neuropeptide hormone activity | IDA | molecular_function |
| GO:0005796 | Golgi lumen | IDA | cellular_component |
| GO:0007631 | feeding behavior | TAS | biological_process |
| GO:0005102 | receptor binding | TAS | molecular_function |
| GO:0008343 | adult feeding behavior | IEA | biological_process |
| GO:0009755 | hormone-mediated signaling pathway | IEA | biological_process |
| GO:0005576 | extracellular region | IEA | cellular_component |
| GO:0005615 | extracellular space | IDA | cellular_component |