Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ADAP1_HUMAN
Description:ArfGAP with dual PH domains 1 [Source:HGNC Symbol;Acc:16486]
Location:chr7 p22.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T276RKRWFtMDDRRPHPhosphoSitePlus
Y232AARFHyLQVAFPhosphoSitePlus
S87RARFEsKVPSFPRKCAHPRD
S87RARFEsKVPSFPRKCEHPRD
T276RKRWFtMDDRRPRKCEHPRD
S87RARFEsKVPSFArfGapPhosphoSitePlus
Y284DRRLMyFKDPLPHPhosphoSitePlus
T276RKRWFtMDDRRPRKCAHPRD

Dephosphorylation site
ADAP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265846R110QCOSMICHead and Neck Cancer21798897
ENSP00000265846R110QCOSMICHead and Neck Cancer21798897

Differential expressed protein
ADAP1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ADAP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANADAP1_HUMANkinase -> substrateHPRD
KPCE_HUMANADAP1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
ADAP1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043533inositol 1,3,4,5 tetrakisphosphate bindingTASmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0043087regulation of GTPase activityIMPbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0032312regulation of ARF GTPase activityIEAbiological_process
GO:0008060ARF GTPase activator activityIDAmolecular_function
GO:0005543phospholipid bindingIEAmolecular_function
GO:0005886plasma membraneIDAcellular_component


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