Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ACV1C_HUMAN
Description:activin A receptor, type IC [Source:HGNC Symbol;Acc:18123]
Location:chr2 q24.1
Node attribute:receptor; kinase

Phosphorylation site
ACV1C_HUMAN do not have phosphorylation site.

Dephosphorylation site
ACV1C_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000335139Q108EBIOMARTBreast Cancer21930507, 21930502
ENSP00000243349Q265EBIOMARTBreast Cancer21930507, 21930502
ENSP00000335178Q185EBIOMARTBreast Cancer21930507, 21930502
ENSP00000243349I319NDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000243349W267RGreenman2007, HPILung Cancer16140923, 17344846, 18428421

Differential expressed protein
ACV1C_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ACV1C_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NODAL_HUMANACV1C_HUMANligand -> receptorHPMR
ACV1C_HUMANSMAD2_HUMANkinase -> substrateKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04350TGF-beta signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:1901164negative regulation of trophoblast cell migrationIDAbiological_process
GO:0004675transmembrane receptor protein serine/threonine kiIEAmolecular_function
GO:0030154cell differentiationIDAbiological_process
GO:0046872metal ion bindingICmolecular_function
GO:0006468protein phosphorylationICbiological_process
GO:0038092nodal signaling pathwayIMPbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0032868response to insulin stimulusIEAbiological_process
GO:0042981regulation of apoptotic processIDAbiological_process
GO:0016020membraneIEAcellular_component
GO:0048179activin receptor complexIDAcellular_component
GO:0046676negative regulation of insulin secretionIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0038100nodal bindingIMPmolecular_function
GO:1901383negative regulation of chorionic trophoblast cell IMPbiological_process
GO:0043280positive regulation of cysteine-type endopeptidaseIMPbiological_process
GO:0019915lipid storageIEAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0009749response to glucose stimulusIEAbiological_process
GO:0016361activin receptor activity, type IIDAmolecular_function
GO:0005024transforming growth factor beta-activated receptorIEAmolecular_function
GO:0002021response to dietary excessIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function


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