Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:AAKG3_HUMAN
Description:protein kinase, AMP-activated, gamma 3 non-catalytic subunit [Source:HGNC Symbol;Acc:9387]
Location:chr2 q35
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T323VLHILtHKRLLCBSPhosphoSitePlus
S336LHIFGsLLPRPPhosphoSitePlus

Dephosphorylation site
AAKG3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000436068L331VCOSMICOvarian Cancer21720365
ENSP00000436068R252CCOSMICLung Cancer20668451
ENSP00000233944R252CCOSMICLung Cancer20668451
ENSP00000233944L331VCOSMICOvarian Cancer21720365

Differential expressed protein
AAKG3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
AAKG3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RAF1_HUMANAAKG3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
AAKG3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005978glycogen biosynthetic processIEAbiological_process
GO:0007243intracellular protein kinase cascadeTASbiological_process
GO:0046320regulation of fatty acid oxidationTASbiological_process
GO:0016301kinase activityIEAmolecular_function
GO:0031588AMP-activated protein kinase complexIEAcellular_component
GO:0006633fatty acid biosynthetic processIEAbiological_process
GO:0008286insulin receptor signaling pathwayTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0015758glucose transportIEAbiological_process
GO:0004679AMP-activated protein kinase activityTASmolecular_function
GO:0005829cytosolTAScellular_component
GO:0007050cell cycle arrestTASbiological_process
GO:0019901protein kinase bindingIDAmolecular_function


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