| UniProt/SwissProt ID: | 1A80_HUMAN |
| Description: | major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:4931] |
| Location: | chrHSCHR6_MHC_COX p2 |
| Node attribute: | substrate; ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T167 | MAAQItKRKWE | PhosphoSitePlus | |
| T158 | DLRSWtAADMA | PhosphoSitePlus | |
| Dephosphorylation site |
| 1A80_HUMAN do not have dephosphorylation site. |
| Mutation site |
| 1A80_HUMAN do not have mutation site. |
| Differential expressed protein |
| 1A80_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| 1A80_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| 1A80_HUMAN | KI3L2_HUMAN | ligand -> receptor | HPMR |
| SRC_HUMAN | 1A80_HUMAN | kinase -> substrate | HPRD |
| KPCA_HUMAN | 1A80_HUMAN | kinase -> substrate | HPRD |
| KAP0_HUMAN | 1A80_HUMAN | kinase -> substrate | HPRD |
| 1A80_HUMAN | CD8A_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05320 | Autoimmune thyroid disease |
| hsa04612 | Antigen processing and presentation |
| hsa04514 | Cell adhesion molecules (CAMs) |
| hsa04940 | Type I diabetes mellitus |
| hsa05330 | Allograft rejection |
| hsa05416 | Viral myocarditis |
| hsa04145 | Phagosome |
| hsa04650 | Natural killer cell mediated cytotoxicity |
| hsa05168 | Herpes simplex infection |
| hsa05332 | Graft-versus-host disease |
| hsa05166 | HTLV-I infection |
| hsa05203 | Viral carcinogenesis |
| hsa05169 | Epstein-Barr virus infection |
| hsa04144 | Endocytosis |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0031901 | early endosome membrane | TAS | cellular_component |
| GO:0002474 | antigen processing and presentation of peptide ant | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0060337 | type I interferon-mediated signaling pathway | TAS | biological_process |
| GO:0042612 | MHC class I protein complex | IEA | cellular_component |
| GO:0071556 | integral to lumenal side of endoplasmic reticulum | TAS | cellular_component |
| GO:0016045 | detection of bacterium | IMP | biological_process |
| GO:0030670 | phagocytic vesicle membrane | TAS | cellular_component |
| GO:0019048 | virus-host interaction | IEA | biological_process |
| GO:0032393 | MHC class I receptor activity | NAS | molecular_function |
| GO:0002479 | antigen processing and presentation of exogenous p | TAS | biological_process |
| GO:0002480 | antigen processing and presentation of exogenous p | TAS | biological_process |
| GO:0005887 | integral to plasma membrane | NAS | cellular_component |
| GO:0050776 | regulation of immune response | TAS | biological_process |
| GO:0060333 | interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0019882 | antigen processing and presentation | IEA | biological_process |
| GO:0042590 | antigen processing and presentation of exogenous p | TAS | biological_process |
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0019221 | cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0012507 | ER to Golgi transport vesicle membrane | TAS | cellular_component |
| GO:0006955 | immune response | IMP | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |