| UniProt/SwissProt ID: | ZN496_HUMAN |
| Description: | zinc finger protein 496 [Source:HGNC Symbol;Acc:23713] |
| Location: | chr1 q44 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S188 | PPSQLsGDPVL | PhosphoSitePlus | |
| S185 | PSRPPsQLSGD | PhosphoSitePlus; phosphoELM | |
| S299 | VSYLDsPSLQP | PhosphoSitePlus | |
| S30 | PGENPsPQGEL | PhosphoSitePlus | |
| S23 | PRKMRsPPGEN | PhosphoSitePlus | |
| Dephosphorylation site |
| ZN496_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000294753 | E344Q | COSMIC | Ovarian Cancer | 21720365 | ENSP00000294753 | K496R | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000294753 | L486P | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000294753 | G26E | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| ZN496_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZN496_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NEK4_HUMAN | ZN496_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ZN496_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016604 | nuclear body | IEA | cellular_component |
| GO:0003677 | DNA binding | ISS | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0016032 | viral reproduction | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0005634 | nucleus | ISS | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0043621 | protein self-association | IEA | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | ISS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |