Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZN496_HUMAN
Description:zinc finger protein 496 [Source:HGNC Symbol;Acc:23713]
Location:chr1 q44
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S188PPSQLsGDPVLPhosphoSitePlus
S185PSRPPsQLSGDPhosphoSitePlus; phosphoELM
S299VSYLDsPSLQPPhosphoSitePlus
S30PGENPsPQGELPhosphoSitePlus
S23PRKMRsPPGENPhosphoSitePlus

Dephosphorylation site
ZN496_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000294753E344QCOSMICOvarian Cancer21720365
ENSP00000294753K496RBIOMARTBreast Cancer21930507, 21930502
ENSP00000294753L486PBIOMARTBreast Cancer21930507, 21930502
ENSP00000294753G26ECOSMICSkin Cancer21984974

Differential expressed protein
ZN496_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZN496_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEK4_HUMANZN496_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
ZN496_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016604nuclear bodyIEAcellular_component
GO:0003677DNA bindingISSmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0016032viral reproductionIEAbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005634nucleusISScellular_component
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005622intracellularIEAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0043621protein self-associationIEAmolecular_function
GO:0045893positive regulation of transcription, DNA-dependenISSbiological_process
GO:0003677DNA bindingIEAmolecular_function


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