Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZIC2_HUMAN
Description:Zic family member 2 [Source:HGNC Symbol;Acc:12873]
Location:chr13 q32.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T358HKRTHtGEKPFPhosphoSitePlus
S199YRQVAsPRTDPPhosphoSitePlus; HPRD
S24RHHHHsAAAAAPhosphoSitePlus
T276KSCNKtFSTMHPhosphoSitePlus
S278CNKTFsTMHELPhosphoSitePlus
T356KIHKRtHTGEKzf-C2H2PhosphoSitePlus
S267DPEQLsNPKKSPhosphoSitePlus
T328HIRVHtGEKPFPhosphoSitePlus

Dephosphorylation site
ZIC2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000365514G359WCOSMICHead and Neck Cancer21798893
ENSP00000365514V301IBIOMARTHepatocellular Carcinoma21930507, 21930502

Differential expressed protein
ZIC2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZIC2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZIC2_HUMANAPOE_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
ZIC2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051091positive regulation of sequence-specific DNA bindiISSbiological_process
GO:0051091positive regulation of sequence-specific DNA bindiIEAbiological_process
GO:0007399nervous system developmentIEAbiological_process
GO:0007417central nervous system developmentIEAbiological_process
GO:0007601visual perceptionISSbiological_process
GO:0005737cytoplasmISScellular_component
GO:0001843neural tube closureIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0031490chromatin DNA bindingISSmolecular_function
GO:0031290retinal ganglion cell axon guidanceIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0045893positive regulation of transcription, DNA-dependenISSbiological_process
GO:0007601visual perceptionIEAbiological_process
GO:0005622intracellularIEAcellular_component
GO:0048066developmental pigmentationIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0003677DNA bindingISSmolecular_function
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0003700sequence-specific DNA binding transcription factorISSmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0007420brain developmentTASbiological_process
GO:0005634nucleusISScellular_component
GO:0045892negative regulation of transcription, DNA-dependenISSbiological_process
GO:0005634nucleusIEAcellular_component
GO:0030154cell differentiationIEAbiological_process
GO:0031490chromatin DNA bindingIEAmolecular_function


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