| UniProt/SwissProt ID: | ZEP1_HUMAN |
| Description: | human immunodeficiency virus type I enhancer binding protein 1 [Source:HGNC Symbol;Acc:4920] |
| Location: | chr6 p24.1 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S492 | SDVEDsGESEE | HPRD | |
| S1050 | NESGTsPKSSE | phosphoELM; SysPTM | |
| S785 | IDSPKsYIFKD | HPRD | |
| S476 | GGLFLsHESPK | HPRD | |
| S681 | FSRSEsADQTV | HPRD | |
| S537 | SFTPSsPENVI | HPRD | |
| S2341 | AAAEHsPQTAA | HPRD | |
| S1735 | SVGRLsPQQES | HPRD | |
| S779 | LSRRGsIDSPK | HPRD | |
| T575 | VSPLRtDSPKA | HPRD | |
| S484 | SPKALsIHSDV | HPRD | |
| S571 | HHVTVsPLRTD | HPRD | |
| S1753 | LSPANsLDIAM | HPRD | |
| S495 | EDSGEsEEEGA | HPRD | |
| T569 | VVHHVtVSPLR | HPRD | |
| S1036 | RRKMKsVGDDE | HPRD | |
| S577 | PLRTDsPKAMD | HPRD | |
| S1051 | NESGTsPKSSE | HPRD | |
| S479 | FLSHEsPKALS | HPRD | |
| S1749 | SKRMLsPANSL | HPRD | |
| S2353 | MPSVAsPHPDP | HPRD | |
| T429 | HIRSHtGERPY | HPRD | |
| S791 | YIFKDsFQFDL | HPRD | |
| S782 | RGSIDsPKSYI | HPRD | |
| Dephosphorylation site |
| ZEP1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000368698 | F1388L | BIOMART | Neoplasms by Histologic Type | 21930507, 21930502 | ENSP00000368698 | A852V | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000368698 | E1879* | BIOMART | Hepatocellular Carcinoma | 21930507, 21930502 | ENSP00000368698 | F1567L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000368698 | V1644D | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000368698 | K453E | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000368698 | S1569L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000368698 | R862K | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000368698 | G916R | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| ZEP1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZEP1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZEP1_HUMAN | IFNB_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| ZEP1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0045892 | negative regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |