| UniProt/SwissProt ID: | ZBT7A_HUMAN |
| Description: | zinc finger and BTB domain containing 7A [Source:HGNC Symbol;Acc:18078] |
| Location: | chr19 p13.3 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T405 | HIRTHtGEKPY | PhosphoSitePlus | |
| T517 | PGATAtPGAPA | PhosphoSitePlus | |
| T515 | PSPGAtATPGA | PhosphoSitePlus; HPRD; phosphoELM | |
| S526 | PAQPSsPDARR | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S337 | AAAGDsDEESR | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S511 | GAPDPsPGATA | PhosphoSitePlus; HPRD; phosphoELM | |
| S525 | APAQPsSPDAR | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S341 | DSDEEsRADDK | PhosphoSitePlus; HPRD | |
| S239 | GDEGDsNPGLW | PhosphoSitePlus | |
| T403 | PRHIRtHTGEK | PhosphoSitePlus | |
| S549 | DEDVAsPDGLG | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Dephosphorylation site |
| ZBT7A_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000323670 | E115* | COSMIC | Pancreatic Cancer | ENSP00000323670 | Y466D | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| ZBT7A_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZBT7A_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZBT7A_HUMAN | MYC_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| ZBT7A_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0035035 | histone acetyltransferase binding | IEA | molecular_function |
| GO:0030154 | cell differentiation | IEA | biological_process |
| GO:0045892 | negative regulation of transcription, DNA-dependen | ISS | biological_process |
| GO:0035035 | histone acetyltransferase binding | ISS | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0045892 | negative regulation of transcription, DNA-dependen | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0000122 | negative regulation of transcription from RNA poly | IEA | biological_process |
| GO:0003677 | DNA binding | ISS | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0007275 | multicellular organismal development | IEA | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |