Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ZBT16_HUMAN
Description:zinc finger and BTB domain containing 16 [Source:HGNC Symbol;Acc:12930]
Location:chr11 q23.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S184PMVDQsPSVSTPDK1RegPhos
S76TLDFLsPKTFQPDK1RegPhos
T597HYRVHtGEKPFzf-H2C2_2PhosphoSitePlus
S197GLSAMsPTKAAPhosphoSitePlus
S628THNGAsPYQCTPDK1RegPhos
S197GLSAMsPTKAAPDK1RegPhos
Y334KHLGIySVLPNPhosphoSitePlus
T282KEGPGtPTRSSPhosphoSitePlus
S407IGEQCsVCGVEHPRD
T282KEGPGtPTRSSPDK1RegPhos
S256VPSQDsPGAAEPDK1RegPhos
T569HKRIHtGEKPYzf-H2C2_2PhosphoSitePlus
T401KSESRtIGEQCHPRD

Dephosphorylation site
ZBT16_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000338157A138VCOSMICCentral Nervous System Neoplasms18772396
ENSP00000338157D270ETCGAOvarian Cancer21720365, 18772890
ENSP00000376721V490IBIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000338157L425QCOSMICHead and Neck Cancer21984974
ENSP00000376721A138VBIOMARTNeoplasms by Histologic Type21930507, 21930502
ENSP00000338157E510KCOSMICMelanoma21499247
ENSP00000376721D270ETCGAOvarian Cancer21720365, 18772890
ENSP00000338157M649ICOSMICHead and Neck Cancer21798893

Differential expressed protein
ZBT16_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ZBT16_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PDPK1_HUMANZBT16_HUMANkinase -> substrateRegPhos
MK08_HUMANZBT16_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05200Pathways in cancer
hsa05202Transcriptional misregulation in cancer
hsa05221Acute myeloid leukemia

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030099myeloid cell differentiationTASbiological_process
GO:0003677DNA bindingIDAmolecular_function
GO:0035136forelimb morphogenesisIEAbiological_process
GO:0017053transcriptional repressor complexIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0001501skeletal system developmentIEAbiological_process
GO:0045638negative regulation of myeloid cell differentiatioIEAbiological_process
GO:0009952anterior/posterior pattern specificationIEAbiological_process
GO:0016567protein ubiquitinationIEAbiological_process
GO:0008285negative regulation of cell proliferationIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0035137hindlimb morphogenesisIEAbiological_process
GO:0048133male germ-line stem cell divisionIEAbiological_process
GO:0061036positive regulation of cartilage developmentIDAbiological_process
GO:0042802identical protein bindingIPImolecular_function
GO:0032332positive regulation of chondrocyte differentiationIMPbiological_process
GO:0016607nuclear speckIDAcellular_component
GO:0042803protein homodimerization activityIDAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0035116embryonic hindlimb morphogenesisIEAbiological_process
GO:0045600positive regulation of fat cell differentiationIMPbiological_process
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0009880embryonic pattern specificationIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0016605PML bodyIDAcellular_component
GO:0006915apoptotic processNASbiological_process
GO:0007417central nervous system developmentIEAbiological_process
GO:0030097hemopoiesisIEAbiological_process
GO:0051216cartilage developmentIDAbiological_process
GO:0016604nuclear bodyIDAcellular_component
GO:0005622intracellularIEAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0001823mesonephros developmentIEAbiological_process
GO:0045778positive regulation of ossificationIDAbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23