Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:XCL1_HUMAN
Description:chemokine (C motif) ligand 1 [Source:HGNC Symbol;Acc:10645]
Location:chr1 q24.2
Node attribute:ligand; PPI(source)

Phosphorylation site
XCL1_HUMAN do not have phosphorylation site.

Dephosphorylation site
XCL1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000356792T100ICOSMICHead and Neck Cancer21798893

Differential expressed protein
XCL1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
XCL1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
XCL1_HUMANXCR1_HUMANligand -> receptorHPMR
XCL1_HUMANXCR1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04062Chemokine signaling pathway
hsa04060Cytokine-cytokine receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007165signal transductionICbiological_process
GO:2000513positive regulation of granzyme A productionIDAbiological_process
GO:0005615extracellular spaceISScellular_component
GO:0032733positive regulation of interleukin-10 productionIDAbiological_process
GO:0002826negative regulation of T-helper 1 type immune respICbiological_process
GO:2000412positive regulation of thymocyte migrationISSbiological_process
GO:0002725negative regulation of T cell cytokine productionIDAbiological_process
GO:0002726positive regulation of T cell cytokine productionISSbiological_process
GO:0042379chemokine receptor bindingNASmolecular_function
GO:0090023positive regulation of neutrophil chemotaxisISSbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:2000503positive regulation of natural killer cell chemotaIDAbiological_process
GO:0051209release of sequestered calcium ion into cytosolISSbiological_process
GO:0071663positive regulation of granzyme B productionIDAbiological_process
GO:0032689negative regulation of interferon-gamma productionIDAbiological_process
GO:2000566positive regulation of CD8-positive, alpha-beta T IDAbiological_process
GO:0042803protein homodimerization activityIDAmolecular_function
GO:2000558positive regulation of immunoglobulin production iISSbiological_process
GO:2000518negative regulation of T-helper 1 cell activationIDAbiological_process
GO:0071636positive regulation of transforming growth factor IDAbiological_process
GO:2000538positive regulation of B cell chemotaxisISSbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0043433negative regulation of sequence-specific DNA bindiIDAbiological_process
GO:0002690positive regulation of leukocyte chemotaxisISSbiological_process
GO:0006955immune responseIEAbiological_process
GO:0007267cell-cell signalingIDAbiological_process
GO:0009615response to virusIDAbiological_process
GO:0035782mature natural killer cell chemotaxisIDAbiological_process
GO:0051281positive regulation of release of sequestered calcIDAbiological_process
GO:0050727regulation of inflammatory responseIDAbiological_process
GO:2000553positive regulation of T-helper 2 cell cytokine prISSbiological_process
GO:0008009chemokine activityIDAmolecular_function
GO:0010820positive regulation of T cell chemotaxisIDAbiological_process
GO:2000563positive regulation of CD4-positive, alpha-beta T ISSbiological_process
GO:0071560cellular response to transforming growth factor beISSbiological_process
GO:0032703negative regulation of interleukin-2 productionIDAbiological_process
GO:2000556positive regulation of T-helper 1 cell cytokine prISSbiological_process
GO:2000562negative regulation of CD4-positive, alpha-beta T IDAbiological_process
GO:0071353cellular response to interleukin-4ISSbiological_process
GO:0001916positive regulation of T cell mediated cytotoxicitIDAbiological_process
GO:0030593neutrophil chemotaxisTASbiological_process