Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:WNT11_HUMAN
Description:wingless-type MMTV integration site family, member 11 [Source:HGNC Symbol;Acc:12776]
Location:chr11 q13.5
Node attribute:ligand; PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S204QALRAsLEMKCwntPhosphoSitePlus
S308SNGSDsCDLMCwntPhosphoSitePlus
S31KWLALsKTPSAPhosphoSitePlus
T340WCCYVtCRRCEwntPhosphoSitePlus
Y338YHWCCyVTCRRwntPhosphoSitePlus
S306KTSNGsDSCDLwntPhosphoSitePlus
S194MRLHNsEVGRQwntPhosphoSitePlus
Y333RCHCKyHWCCYwntPhosphoSitePlus

Dephosphorylation site
WNT11_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000325526N304SCOSMICLung Cancer20668451
ENSP00000325526R221CCOSMICSkin Cancer21984974
ENSP00000325526C344YCOSMICOvarian Cancer21720365

Differential expressed protein
WNT11_HUMAN is not differential expressed protein.

Hyperphosphorylation site
WNT11_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
WNT11_HUMANFZD7_HUMANligand -> receptorHPMR
WNT11_HUMANFZD10_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04340Hedgehog signaling pathway
hsa04916Melanogenesis
hsa04310Wnt signaling pathway
hsa05217Basal cell carcinoma
hsa05166HTLV-I infection
hsa05200Pathways in cancer

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0035567non-canonical Wnt receptor signaling pathwayIEAbiological_process
GO:0090037positive regulation of protein kinase C signaling IMPbiological_process
GO:0034394protein localization to cell surfaceIMPbiological_process
GO:0003151outflow tract morphogenesisIBAbiological_process
GO:0032915positive regulation of transforming growth factor IEAbiological_process
GO:0032915positive regulation of transforming growth factor IBAbiological_process
GO:0030325adrenal gland developmentIEPbiological_process
GO:0005615extracellular spaceIBAcellular_component
GO:0043066negative regulation of apoptotic processIMPbiological_process
GO:0060484lung-associated mesenchyme developmentIEPbiological_process
GO:0016055Wnt receptor signaling pathwayIEAbiological_process
GO:0009798axis specificationIBAbiological_process
GO:0030295protein kinase activator activityIMPmolecular_function
GO:0006468protein phosphorylationIMPbiological_process
GO:0090090negative regulation of canonical Wnt receptor signIEAbiological_process
GO:0001822kidney developmentIEAbiological_process
GO:0030336negative regulation of cell migrationIMPbiological_process
GO:0044212transcription regulatory region DNA bindingIDAmolecular_function
GO:0070830tight junction assemblyIBAbiological_process
GO:0048844artery morphogenesisIEAbiological_process
GO:0030182neuron differentiationISSbiological_process
GO:0051496positive regulation of stress fiber assemblyIMPbiological_process
GO:0005576extracellular regionIEAcellular_component
GO:0030335positive regulation of cell migrationIMPbiological_process
GO:0090272negative regulation of fibroblast growth factor prIEAbiological_process
GO:0032320positive regulation of Ras GTPase activityIMPbiological_process
GO:0072201negative regulation of mesenchymal cell proliferatIEAbiological_process
GO:0060070canonical Wnt receptor signaling pathwayIEAbiological_process
GO:0031012extracellular matrixIEAcellular_component
GO:0072177mesonephric duct developmentIEPbiological_process
GO:0001664G-protein coupled receptor bindingIBAmolecular_function
GO:0071300cellular response to retinoic acidISSbiological_process
GO:0005578proteinaceous extracellular matrixIEAcellular_component
GO:0045893positive regulation of transcription, DNA-dependenIMPbiological_process
GO:0060021palate developmentIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0030308negative regulation of cell growthIMPbiological_process
GO:0048706embryonic skeletal system developmentIEPbiological_process
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0061037negative regulation of cartilage developmentNASbiological_process
GO:0009952anterior/posterior pattern specificationIBAbiological_process
GO:0060548negative regulation of cell deathIMPbiological_process
GO:0060412ventricular septum morphogenesisIEAbiological_process
GO:0060675ureteric bud morphogenesisIEPbiological_process
GO:0030282bone mineralizationIEAbiological_process
GO:0030282bone mineralizationIBAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0060021palate developmentIMPbiological_process
GO:0060412ventricular septum morphogenesisIBAbiological_process
GO:0048844artery morphogenesisIBAbiological_process
GO:0005886plasma membraneIBAcellular_component
GO:0090090negative regulation of canonical Wnt receptor signIMPbiological_process
GO:0001649osteoblast differentiationIEAbiological_process
GO:0003151outflow tract morphogenesisIEAbiological_process
GO:0005102receptor bindingIEAmolecular_function
GO:0070830tight junction assemblyIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0061101neuroendocrine cell differentiationIMPbiological_process
GO:0010628positive regulation of gene expressionIMPbiological_process
GO:0001649osteoblast differentiationIBAbiological_process
GO:0045860positive regulation of protein kinase activityIMPbiological_process
GO:0060197cloacal septationIEPbiological_process
GO:0007492endoderm developmentIBAbiological_process
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0005099Ras GTPase activator activityIMPmolecular_function
GO:0045892negative regulation of transcription, DNA-dependenIMPbiological_process