Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:WIPF1_HUMAN
Description:WAS/WASL interacting protein family, member 1 [Source:HGNC Symbol;Acc:12736]
Location:chr2 q31.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S340PQRNLsLSSSTPhosphoSitePlus; HPRD
S343NLSLSsSTPPLHPRD
S234ALGGGsIRQSPPhosphoSitePlus
S350TPPLPsPGRSGPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T345SLSSStPPLPSPhosphoSitePlus; HPRD; phosphoELM
S214GPRQPsPGPTPPhosphoSitePlus
S344LSLSSsTPPLPPhosphoSitePlus; HPRD; phosphoELM
T398RALPAtPQLPSPhosphoSitePlus
S488ESRSGsNRRERPKCt(PKC thetaRegPhos
S488ESRSGsNRRERPKC_thetaphosphoELM
S488ESRSGsNRRERPhosphoSitePlus
S142SAKPFsPPSGPPhosphoSitePlus
S488ESRSGsNRRERPKCtRegPhos
S154RFPVPsPGHRSPhosphoSitePlus
S488ESRSGsNRRERPRKCQHPRD
S91GGGGGsFGGGGGRPPhosphoSitePlus
S276VGNRPsIHREAPhosphoSitePlus

Dephosphorylation site
WIPF1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000352802D181GBIOMARTBreast Cancer21930507, 21930502
ENSP00000386431D181GBIOMARTBreast Cancer21930507, 21930502
ENSP00000376329D371ECOSMICOvarian Cancer21720365
ENSP00000376329D181GBIOMARTBreast Cancer21930507, 21930502
ENSP00000376330D181GBIOMARTBreast Cancer21930507, 21930502
ENSP00000272746D181GBIOMARTBreast Cancer21930507, 21930502
ENSP00000376329G90ECOSMICMelanoma21499247

Differential expressed protein
WIPF1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
WIPF1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANWIPF1_HUMANkinase -> substrateRegPhos
KPCT_HUMANWIPF1_HUMANkinase -> substrateHPRD; NetPath; Robert H Newman (2013)

Function Annotation
KEGG Pathway
WIPF1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0046827positive regulation of protein export from nucleusIEAbiological_process
GO:0005884actin filamentIEAcellular_component
GO:0008154actin polymerization or depolymerizationTASbiological_process
GO:0015629actin cytoskeletonIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0030048actin filament-based movementIEAbiological_process
GO:0003779actin bindingIEAmolecular_function
GO:0015629actin cytoskeletonTAScellular_component
GO:0006461protein complex assemblyTASbiological_process
GO:0030036actin cytoskeleton organizationIEAbiological_process
GO:0005522profilin bindingTASmolecular_function
GO:0016023cytoplasmic membrane-bounded vesicleIEAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23