Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:WEE2_HUMAN
Description:WEE1 homolog 2 (S. pombe) [Source:HGNC Symbol;Acc:19684]
Location:chr7 q34
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T83DQILRtPVSHPPhosphoSitePlus
T509KFKTAtLERELPhosphoSitePlus
S102QPDSRsKLLPSPhosphoSitePlus

Dephosphorylation site
WEE2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000380675R398HHPIOvarian Cancer17344846
ENSP00000380675N332KHPIGastric Cancer17344846

Differential expressed protein
WEE2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
WEE2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
WEE2_HUMANCDK1_HUMANkinase -> substrateKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04110Cell cycle

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0007343egg activationIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0004715non-membrane spanning protein tyrosine kinase actiIEAmolecular_function
GO:0035038female pronucleus assemblyISSbiological_process
GO:0060631regulation of meiosis IISSbiological_process
GO:0007143female meiosisISSbiological_process
GO:0035038female pronucleus assemblyIEAbiological_process
GO:0007128meiotic prophase IISSbiological_process
GO:0060283negative regulation of oocyte developmentISSbiological_process
GO:0060631regulation of meiosis IIEAbiological_process
GO:0006468protein phosphorylationIEAbiological_process
GO:0007128meiotic prophase IIEAbiological_process
GO:0000287magnesium ion bindingIEAmolecular_function
GO:0060283negative regulation of oocyte developmentIEAbiological_process
GO:0007137meiotic metaphase IIISSbiological_process
GO:0007137meiotic metaphase IIIEAbiological_process
GO:0007343egg activationISSbiological_process
GO:0007067mitosisIEAbiological_process
GO:0005813centrosomeIDAcellular_component
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0007143female meiosisIEAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0004672protein kinase activityIEAmolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0005737cytoplasmIEAcellular_component


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