Phosphorylation

Protein information

UniProt/SwissProt ID:	WEE2_HUMAN
Description:	WEE1 homolog 2 (S. pombe) [Source:HGNC Symbol;Acc:19684]
Location:	chr7 q34
Node attribute:	kinase

Position	PhosphoPeptide	Source
T83	DQILRtPVSHP	PhosphoSitePlus
T509	KFKTAtLEREL	PhosphoSitePlus
S102	QPDSRsKLLPS	PhosphoSitePlus

WEE2_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000380675	R398H	HPI	Ovarian Cancer	17344846
ENSP00000380675	N332K	HPI	Gastric Cancer	17344846

WEE2_HUMAN is not differential expressed protein.

WEE2_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
WEE2_HUMAN	CDK1_HUMAN	kinase -> substrate	KEGG

KEGG Pathway

KEGG ID	Pathway
hsa04110	Cell cycle

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0004713	protein tyrosine kinase activity	IEA	molecular_function
GO:0007343	egg activation	IEA	biological_process
GO:0005524	ATP binding	IEA	molecular_function
GO:0004715	non-membrane spanning protein tyrosine kinase acti	IEA	molecular_function
GO:0035038	female pronucleus assembly	ISS	biological_process
GO:0060631	regulation of meiosis I	ISS	biological_process
GO:0007143	female meiosis	ISS	biological_process
GO:0035038	female pronucleus assembly	IEA	biological_process
GO:0007128	meiotic prophase I	ISS	biological_process
GO:0060283	negative regulation of oocyte development	ISS	biological_process
GO:0060631	regulation of meiosis I	IEA	biological_process
GO:0006468	protein phosphorylation	IEA	biological_process
GO:0007128	meiotic prophase I	IEA	biological_process
GO:0000287	magnesium ion binding	IEA	molecular_function
GO:0060283	negative regulation of oocyte development	IEA	biological_process
GO:0007137	meiotic metaphase II	ISS	biological_process
GO:0007137	meiotic metaphase II	IEA	biological_process
GO:0007343	egg activation	ISS	biological_process
GO:0007067	mitosis	IEA	biological_process
GO:0005813	centrosome	IDA	cellular_component
GO:0016772	transferase activity, transferring phosphorus-cont	IEA	molecular_function
GO:0007143	female meiosis	IEA	biological_process
GO:0005737	cytoplasm	IDA	cellular_component
GO:0004672	protein kinase activity	IEA	molecular_function
GO:0004674	protein serine/threonine kinase activity	IEA	molecular_function
GO:0005634	nucleus	IDA	cellular_component
GO:0005737	cytoplasm	IEA	cellular_component

Human Phosphorylation Mediated
Signaling Transduction Network