| UniProt/SwissProt ID: | VPS72_HUMAN |
| Description: | vacuolar protein sorting 72 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:11644] |
| Location: | chr1 q21.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y326 | EAYKKyITAHG | PhosphoSitePlus | |
| T335 | HGLPPtASALG | PhosphoSitePlus | |
| S132 | SDSRKsMRQST | PKC_group | phosphoELM |
| T168 | CERPLtQEELL | YL1 | PhosphoSitePlus |
| T86 | KRRVVtKAYKE | CaM-KII_group | phosphoELM |
| T137 | SMRQStAEHTR | CaM-KII_group | phosphoELM |
| S41 | GFTEEsGDDEY | CK2_group | phosphoELM |
| S108 | TPAGSsQKARE | YL1 | PhosphoSitePlus |
| S71 | GDEPSsDGEAE | CK2_group | phosphoELM |
| T168 | CERPLtQEELL | CaM-KII_group | phosphoELM |
| S337 | LPPTAsALGPG | PhosphoSitePlus | |
| S59 | EDEVDsDFDID | CK2_group | phosphoELM |
| S51 | YQGDQsDTEDE | CK2_group | phosphoELM |
| T168 | CERPLtQEELL | phosphoELM | |
| Dephosphorylation site |
| VPS72_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000357887 | I318V | BIOMART, HPI | Breast Cancer | 21930507, 21930502, 16959974 |
| Differential expressed protein |
| VPS72_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| VPS72_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KCC4_HUMAN | VPS72_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| VPS72_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0043234 | protein complex | IDA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0000122 | negative regulation of transcription from RNA poly | TAS | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0016568 | chromatin modification | IEA | biological_process |
| GO:0035019 | somatic stem cell maintenance | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |