Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:VAMP3_HUMAN
Description:vesicle-associated membrane protein 3 [Source:HGNC Symbol;Acc:12644]
Location:chr1 p36.23
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S63SQFETsAAKLKHPRD
T3___MStGPTAAPhosphoSitePlus
S58LQAGAsQFETSHPRD; phosphoELM; SysPTM
S44RDQKLsELDDRSynaptobrevinPhosphoSitePlus
S11TAATGsNRRLQSynaptobrevinPhosphoSitePlus; SysPTM
S58LQAGAsQFETSSynaptobrevinPhosphoSitePlus; SysPTM
S11TAATGsNRRLQHPRD; SysPTM
T3PTAAHPRD
S2____MsTGPTAPhosphoSitePlus
S63SQFETsAAKLKSynaptobrevinPhosphoSitePlus
S44RDQKLsELDDRHPRD
T18RRLQQtQNQVDSynaptobrevinPhosphoSitePlus

Dephosphorylation site
VAMP3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000054666E61QBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000054666Testicular CancerNormal vs. Cancercell lineDown18489135

Hyperphosphorylation site
VAMP3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK16_HUMANVAMP3_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
VAMP3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0034446substrate adhesion-dependent cell spreadingIEAbiological_process
GO:0031410cytoplasmic vesicleIEAcellular_component
GO:0045202synapseIEAcellular_component
GO:0030665clathrin-coated vesicle membraneIEAcellular_component
GO:0005886plasma membraneISScellular_component
GO:0006944cellular membrane fusionTASbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0034446substrate adhesion-dependent cell spreadingISSbiological_process
GO:0030141secretory granuleIEAcellular_component
GO:0016324apical plasma membraneIEAcellular_component
GO:0006887exocytosisTASbiological_process
GO:0043005neuron projectionIEAcellular_component
GO:0055037recycling endosomeIDAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0043231intracellular membrane-bounded organelleIEAcellular_component
GO:0016192vesicle-mediated transportIEAbiological_process
GO:0017075syntaxin-1 bindingIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0017156calcium ion-dependent exocytosisIEAbiological_process
GO:0006461protein complex assemblyIEAbiological_process
GO:0001921positive regulation of receptor recyclingIEAbiological_process
GO:0001921positive regulation of receptor recyclingISSbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0000149SNARE bindingIEAmolecular_function
GO:0006904vesicle docking involved in exocytosisTASbiological_process
GO:0030054cell junctionIEAcellular_component
GO:0031201SNARE complexIEAcellular_component
GO:0042147retrograde transport, endosome to GolgiIDAbiological_process
GO:0055037recycling endosomeIEAcellular_component
GO:0030136clathrin-coated vesicleIDAcellular_component
GO:0043229intracellular organelleIEAcellular_component
GO:0043001Golgi to plasma membrane protein transportIEAbiological_process


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