Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:USO1_HUMAN
Description:USO1 vesicle transport factor [Source:HGNC Symbol;Acc:30904]
Location:chr4 q21.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T465RVQLAtSIGNPUso1_p115_headPhosphoSitePlus
S483CTNILsQGSKIUso1_p115_headPhosphoSitePlus
S952DEDDEsEDPGKphosphoELM
S32CDRVAsSTLLDPhosphoSitePlus
S952DEDDEsEDPGKUso1_p115_CPhosphoSitePlus
S942EDELEsGDQEDUso1_p115_CPhosphoSitePlus
S50ALKSLsKKYRLPhosphoSitePlus
S486ILSQGsKIQTRUso1_p115_headPhosphoSitePlus
Y718QHQGSySEGAQPhosphoSitePlus
Y655NIVTHyKNMIRADIPPhosphoSitePlus
S942EDELEsGDQEDphosphoELM

Dephosphorylation site
USO1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000264904V85LCOSMICOvarian Cancer21720365
ENSP00000264904A250VCOSMICCentral Nervous System Neoplasms
ENSP00000264904M488fs*5COSMICOvarian Cancer21720365
ENSP00000264904P189SCOSMICHead and Neck Cancer21798893
ENSP00000264904I257TCOSMICOvarian Cancer21720365
ENSP00000264904Y487*COSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000264904Breast CancerNormal vs. CancertissueUp0.6720739354
ENSP00000264904Breast CancerNormal vs. CancertissueUp0.6720739354
ENSP00000264904Testicular CancerNormal vs. Cancercell lineUp18489135

Hyperphosphorylation site
USO1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK2B_HUMANUSO1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
USO1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008565protein transporter activityIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0005829cytosolIEAcellular_component
GO:0000139Golgi membraneIEAcellular_component
GO:0005488bindingIEAmolecular_function
GO:0006886intracellular protein transportIEAbiological_process
GO:0016192vesicle-mediated transportIEAbiological_process
GO:0048280vesicle fusion with Golgi apparatusIEAbiological_process


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