Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:UNC5C_HUMAN
Description:unc-5 homolog C (C. elegans) [Source:HGNC Symbol;Acc:12569]
Location:chr4 q22.3
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T674LVGHStTKAAAPhosphoSitePlus
S127VSIEIsRQQVEPhosphoSitePlus
Y454YRGPVyALHDVPhosphoSitePlus
T506LSPQMtQSLLEPhosphoSitePlus
S123IVREVsIEISRPhosphoSitePlus
T832LDPANtITTVTPhosphoSitePlus
S843GPSAFsIPLPIPhosphoSitePlus
S516ENEALsLKNQSPhosphoSitePlus
S521SLKNQsLARQTPhosphoSitePlus
S460ALHDVsDKIPMPhosphoSitePlus

Dephosphorylation site
UNC5C_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000406022R681HBIOMARTBreast Cancer21930507, 21930502
ENSP00000406022A613TBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000406022Y881*BIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
UNC5C_HUMAN is not differential expressed protein.

Hyperphosphorylation site
UNC5C_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NET1_HUMANUNC5C_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04360Axon guidance

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0007411axon guidanceTASbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0030334regulation of cell migrationIEAbiological_process
GO:0007420brain developmentIEAbiological_process
GO:0005042netrin receptor activityIEAmolecular_function
GO:0038007netrin-activated signaling pathwayIEAbiological_process
GO:0006915apoptotic processIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function


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