Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:UBIP1_HUMAN
Description:upstream binding protein 1 (LBP-1a) [Source:HGNC Symbol;Acc:12507]
Location:chr3 p22.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S425SLKSRsVRPRLPhosphoSitePlus; HPRD
T401DLLKLtKEDLVHPRD
T194ISTEFtPRKHGCP2PhosphoSitePlus
Y266KYQPSyDTTILPhosphoSitePlus
Y262HEKEKyQPSYDPhosphoSitePlus
S423YNSLKsRSVRPPhosphoSitePlus; HPRD

Dephosphorylation site
UBIP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000283629E362KBIOMARTBreast Cancer21930507, 21930502
ENSP00000283628P297SCOSMICOvarian Cancer21720365
ENSP00000283629S36ICOSMICOvarian Cancer21720365
ENSP00000283628S36ICOSMICOvarian Cancer21720365
ENSP00000283629Q407*COSMICRenal Cancer20054297
ENSP00000283628Q407*COSMICRenal Cancer20054297
ENSP00000283628E362KBIOMARTBreast Cancer21930507, 21930502
ENSP00000395558E326KBIOMARTBreast Cancer21930507, 21930502
ENSP00000283629P297SCOSMICOvarian Cancer21720365
ENSP00000283628C339FCOSMICRenal Cancer20054297
ENSP00000283629C339FCOSMICRenal Cancer20054297

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000283628hepatitis B virusNormal vs. CancertissueUp6.314726492

Hyperphosphorylation site
UBIP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
UBIP1_HUMANCP11A_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
UBIP1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0019079viral genome replicationTASbiological_process
GO:0005634nucleusTAScellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0001525angiogenesisIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenTASbiological_process
GO:0006357regulation of transcription from RNA polymerase IITASbiological_process
GO:0003700sequence-specific DNA binding transcription factorTASmolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0003714transcription corepressor activityTASmolecular_function


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