| UniProt/SwissProt ID: | UB2D2_HUMAN |
| Description: | ubiquitin-conjugating enzyme E2D 2 [Source:HGNC Symbol;Acc:12475] |
| Location: | chr5 q31.2 |
| Node attribute: | ubiquitination(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y145 | EWTQKyAM___ | PhosphoSitePlus | |
| Dephosphorylation site |
| UB2D2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000381717 | R90* | COSMIC | Central Nervous System Neoplasms | 21163964 | ENSP00000381718 | R90* | COSMIC | Central Nervous System Neoplasms | 21163964 |
| Differential expressed protein |
| UB2D2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| UB2D2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| UB2D2_HUMAN | IKBA_HUMAN | ubiquitination | NetPath |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05131 | Shigellosis |
| hsa04141 | Protein processing in endoplasmic reticulum |
| hsa04120 | Ubiquitin mediated proteolysis |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016881 | acid-amino acid ligase activity | IEA | molecular_function |
| GO:0000209 | protein polyubiquitination | IDA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0071456 | cellular response to hypoxia | TAS | biological_process |
| GO:0033554 | cellular response to stress | TAS | biological_process |
| GO:0006511 | ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0016567 | protein ubiquitination | IDA | biological_process |
| GO:0061418 | regulation of transcription from RNA polymerase II | TAS | biological_process |
| GO:0006464 | cellular protein modification process | TAS | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0004842 | ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0070936 | protein K48-linked ubiquitination | IDA | biological_process |