Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TRPV6_HUMAN
Description:transient receptor potential cation channel, subfamily V, member 6 [Source:HGNC Symbol;Acc:14006]
Location:chr7 q34
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T702RLRQGtLRRDLPKCaRegPhos
T702RLRQGtLRRDLPhosphoSitePlus
T688SVSRStSRSSAPhosphoSitePlus
S144RRASVsARATGAnk_2PhosphoSitePlus
T148VSARAtGTAFRPhosphoSitePlus
T702RLRQGtLRRDLPKCa(PKC alphaRegPhos
T702RLRQGtLRRDLPRKCAHPRD
Y278LTSTLyDLTEIPhosphoSitePlus
Y67NKLLKyEDCKVAnk_2PhosphoSitePlus
S142LARRAsVSARAAnk_2PhosphoSitePlus
T702RLRQGtLRRDLPKC_alphaphosphoELM
T601QIVATtVMLERHPRD; phosphoELM

Dephosphorylation site
TRPV6_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000352358R414HCOSMICOvarian Cancer20826764
ENSP00000352358S683LCOSMICHead and Neck Cancer21798893
ENSP00000352358T298ICOSMICHead and Neck Cancer21798893
ENSP00000352358P672SCOSMICSkin Cancer21984974

Differential expressed protein
TRPV6_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TRPV6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANTRPV6_HUMANkinase -> substrateHPRD; Robert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04978Mineral absorption
hsa04970Salivary secretion

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005516calmodulin bindingIDAmolecular_function
GO:0006816calcium ion transportNASbiological_process
GO:0006811ion transportIEAbiological_process
GO:0005262calcium channel activityIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0006816calcium ion transportIEAbiological_process
GO:0005216ion channel activityIEAmolecular_function
GO:0017158regulation of calcium ion-dependent exocytosisNASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0055085transmembrane transportIEAbiological_process


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