Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TRPM7_HUMAN
Description:transient receptor potential cation channel, subfamily M, member 7 [Source:HGNC Symbol;Acc:17994]
Location:chr15 q21.2
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S1358GALFPsAVSPPPhosphoSitePlus
T1265VHNEItRELSIPhosphoSitePlus
T1508PSTEDtHEVDSPhosphoSitePlus
S1567NLMRLsQSIPFPhosphoSitePlus
S1258KASEAsKVHNEPhosphoSitePlus
S1477LKRVSsLAGFTPhosphoSitePlus; HPRD; phosphoELM
S1779NLTDPsVIKAEAlpha_kinasePhosphoSitePlus
S1860SESTNsVRLMLPhosphoSitePlus
T1830KRNDYtPDKIIPhosphoSitePlus
T523YLMGGtYRCTYPhosphoSitePlus
S57ACFTAsLAMKYPhosphoSitePlus
S1476TLKRVsSLAGFPhosphoSitePlus
S1527LQDRPsNREMPPhosphoSitePlus
T1435TEGDNtEFGAFPhosphoSitePlus
T1537PSEEGtLNGLTPhosphoSitePlus
T12IESTLtKRECVHPRD
S1504ISRRPsTEDTHPhosphoSitePlus
T1417KSHLEtGTKDQPhosphoSitePlus
S1615KIEFLsKEEMGAlpha_kinasePhosphoSitePlus
T1405KFFVStPSQPSPhosphoSitePlus
S1193KFHSGsEERIRPhosphoSitePlus
S1500QAEKIsRRPSTPhosphoSitePlus; HPRD
S1191DDKFHsGSEERPhosphoSitePlus
S1695QMKPKsIPYSPAlpha_kinasePhosphoSitePlus
S1407FVSTPsQPSCKPhosphoSitePlus
T1419HLETGtKDQETPhosphoSitePlus
T1455QRFKEtSNKIKPhosphoSitePlus
T1542TLNGLtSPFKPPhosphoSitePlus
S1404TKFFVsTPSQPPhosphoSitePlus; HPRD
S1569MRLSQsIPFTPPhosphoSitePlus; HPRD
S1598NILNNsMSSWSAlpha_kinasePhosphoSitePlus
S1287GPVRPsVWKKHPhosphoSitePlus
S1255TAQKAsEASKVPhosphoSitePlus
S1543LNGLTsPFKPAPhosphoSitePlus
S907REIFMsEAGKVIon_transPhosphoSitePlus
S1230LQSLDsQIGHLPhosphoSitePlus
S1446VGHRDsMDLQRPhosphoSitePlus
T1163PKLFLtEEDQKPhosphoSitePlus
T1551KPAMDtNYYYSPhosphoSitePlus
T1685AAQKLtFAFNQAlpha_kinasePhosphoSitePlus
T1471NTSENtLKRVSPhosphoSitePlus
S1533NREMPsEEGTLPhosphoSitePlus
S1851LQPGNsTKESEPhosphoSitePlus
S1413QPSCKsHLETGPhosphoSitePlus
S1660VNTWSsIYKEDAlpha_kinasePhosphoSitePlus
T1505SRRPStEDTHEPhosphoSitePlus
S1493SIPVHsKQAEKPhosphoSitePlus
S1468SNNNTsENTLKPhosphoSitePlus
S1271RELSIsKHLAQPhosphoSitePlus
T1583RGEPVtVYRLEPhosphoSitePlus
S1387QKLGSsSTSIPPhosphoSitePlus
S1390GSSSTsIPHLSPhosphoSitePlus
T555NTSSStPQLRKPhosphoSitePlus
S1456RFKETsNKIKIPhosphoSitePlus
T1482SLAGFtDCHRTPhosphoSitePlus
S1463KIKILsNNNTSPhosphoSitePlus
S1513THEVDsKAALIPhosphoSitePlus; HPRD

Dephosphorylation site
TRPM7_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000320239S406CHPIOvarian Cancer17344846
ENSP00000320239M830VHPIGastric Cancer17344846
ENSP00000320239T720SHPIbreast ductal carcinoma17344846

Differential expressed protein
TRPM7_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TRPM7_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TRPM7_HUMANANXA1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04978Mineral absorption

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005216ion channel activityIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0031032actomyosin structure organizationIEAbiological_process
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0006811ion transportIEAbiological_process
GO:0006816calcium ion transportIEAbiological_process
GO:0016340calcium-dependent cell-matrix adhesionIEAbiological_process
GO:0016301kinase activityIEAmolecular_function
GO:0055085transmembrane transportIEAbiological_process
GO:0017022myosin bindingIEAmolecular_function
GO:0001726ruffleIEAcellular_component
GO:0016021integral to membraneIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0046872metal ion bindingIEAmolecular_function
GO:0008219cell deathIEAbiological_process
GO:0005262calcium channel activityIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0046777protein autophosphorylationIEAbiological_process
GO:0003779actin bindingIEAmolecular_function


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