| UniProt/SwissProt ID: | TRIB2_HUMAN |
| Description: | tribbles homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:30809] |
| Location: | chr2 p24.3 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S299 | SERLTsQEILD | Pkinase_CAMK | PhosphoSitePlus |
| T298 | PSERLtSQEIL | Pkinase_CAMK | PhosphoSitePlus |
| Y134 | FFERSyGDMHS | PhosphoSitePlus | |
| S28 | DFEELsSIRSA | PhosphoSitePlus | |
| Y14 | ITIARyGRSRN | PhosphoSitePlus | |
| S139 | YGDMHsFVRTC | Pkinase_CAMK | PhosphoSitePlus |
| S29 | FEELSsIRSAE | PhosphoSitePlus | |
| S133 | VFFERsYGDMH | PhosphoSitePlus | |
| T143 | HSFVRtCKKLR | Pkinase_CAMK | PhosphoSitePlus |
| Dephosphorylation site |
| TRIB2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| TRIB2_HUMAN do not have mutation site. |
| Differential expressed protein |
| TRIB2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TRIB2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TRIB2_HUMAN | BPL1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TRIB2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0045081 | negative regulation of interleukin-10 biosynthetic | IMP | biological_process |
| GO:0006469 | negative regulation of protein kinase activity | NAS | biological_process |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0031625 | ubiquitin protein ligase binding | IEA | molecular_function |
| GO:0008134 | transcription factor binding | IEA | molecular_function |
| GO:0004860 | protein kinase inhibitor activity | IEA | molecular_function |
| GO:0032436 | positive regulation of proteasomal ubiquitin-depen | IEA | biological_process |
| GO:0005737 | cytoplasm | ISS | cellular_component |
| GO:0043405 | regulation of MAP kinase activity | ISS | biological_process |
| GO:0005856 | cytoskeleton | IEA | cellular_component |
| GO:0045599 | negative regulation of fat cell differentiation | IEA | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0055106 | ubiquitin-protein ligase regulator activity | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0004672 | protein kinase activity | IEA | molecular_function |