Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TRIB2_HUMAN
Description:tribbles homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:30809]
Location:chr2 p24.3
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S299SERLTsQEILDPkinase_CAMKPhosphoSitePlus
T298PSERLtSQEILPkinase_CAMKPhosphoSitePlus
Y134FFERSyGDMHSPhosphoSitePlus
S28DFEELsSIRSAPhosphoSitePlus
Y14ITIARyGRSRNPhosphoSitePlus
S139YGDMHsFVRTCPkinase_CAMKPhosphoSitePlus
S29FEELSsIRSAEPhosphoSitePlus
S133VFFERsYGDMHPhosphoSitePlus
T143HSFVRtCKKLRPkinase_CAMKPhosphoSitePlus

Dephosphorylation site
TRIB2_HUMAN do not have dephosphorylation site.

Mutation site
TRIB2_HUMAN do not have mutation site.

Differential expressed protein
TRIB2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TRIB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TRIB2_HUMANBPL1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
TRIB2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045081negative regulation of interleukin-10 biosyntheticIMPbiological_process
GO:0006469negative regulation of protein kinase activityNASbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0031625ubiquitin protein ligase bindingIEAmolecular_function
GO:0008134transcription factor bindingIEAmolecular_function
GO:0004860protein kinase inhibitor activityIEAmolecular_function
GO:0032436positive regulation of proteasomal ubiquitin-depenIEAbiological_process
GO:0005737cytoplasmISScellular_component
GO:0043405regulation of MAP kinase activityISSbiological_process
GO:0005856cytoskeletonIEAcellular_component
GO:0045599negative regulation of fat cell differentiationIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0055106ubiquitin-protein ligase regulator activityIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0004672protein kinase activityIEAmolecular_function


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