| UniProt/SwissProt ID: | TRI36_HUMAN |
| Description: | tripartite motif containing 36 [Source:HGNC Symbol;Acc:16280] |
| Location: | chr5 q22.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y585 | VEPYSyLVKVG | SPRY | PhosphoSitePlus |
| Y583 | FRVEPySYLVK | SPRY | PhosphoSitePlus |
| S177 | MDCSAsYCNEC | zf-B_box | PhosphoSitePlus |
| S170 | QESTKsCMDCS | zf-B_box | PhosphoSitePlus |
| Y178 | DCSASyCNECF | zf-B_box | PhosphoSitePlus |
| S175 | SCMDCsASYCN | zf-B_box | PhosphoSitePlus |
| Y253 | TMSSAyKTLKE | PhosphoSitePlus | |
| Dephosphorylation site |
| TRI36_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000282369 | K720R | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000282369 | Q195* | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000282369 | V429I | COSMIC | Ovarian Cancer | 21720365 | ENSP00000282369 | P162L | COSMIC | Ovarian Cancer | 21720365 | ENSP00000282369 | E143V | COSMIC | Ovarian Cancer | 21720365 | ENSP00000282369 | S447C | COSMIC | Lung Cancer | ENSP00000282369 | Q376E | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| TRI36_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TRI36_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ANPRB_HUMAN | TRI36_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| EPHA3_HUMAN | TRI36_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TRI36_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005856 | cytoskeleton | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007340 | acrosome reaction | IEA | biological_process |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0016874 | ligase activity | IEA | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0001669 | acrosomal vesicle | IEA | cellular_component |