| UniProt/SwissProt ID: | TR11B_HUMAN |
| Description: | tumor necrosis factor receptor superfamily, member 11b [Source:HGNC Symbol;Acc:11909] |
| Location: | chr8 q24.12 |
| Node attribute: | receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T362 | FPKTVtQSLKK | Death | PhosphoSitePlus |
| T360 | YHFPKtVTQSL | Death | PhosphoSitePlus |
| S364 | KTVTQsLKKTI | Death | PhosphoSitePlus |
| S246 | KRQHSsQEQTF | Death | PhosphoSitePlus |
| Dephosphorylation site |
| TR11B_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000297350 | R111C | COSMIC | Central Nervous System Neoplasms | 18772890 |
| Differential expressed protein |
| TR11B_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TR11B_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNF11_HUMAN | TR11B_HUMAN | ligand -> receptor | HPMR |
| TNF11_HUMAN | TR11B_HUMAN | other | KEGG |
| TNF10_HUMAN | TR11B_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04380 | Osteoclast differentiation |
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0042493 | response to drug | IEA | biological_process |
| GO:0030198 | extracellular matrix organization | IEA | biological_process |
| GO:0005576 | extracellular region | TAS | cellular_component |
| GO:0007584 | response to nutrient | IEA | biological_process |
| GO:0006915 | apoptotic process | IEA | biological_process |
| GO:0032026 | response to magnesium ion | IEA | biological_process |
| GO:0005578 | proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0010035 | response to inorganic substance | IEA | biological_process |
| GO:0004872 | receptor activity | TAS | molecular_function |
| GO:0042489 | negative regulation of odontogenesis of dentin-con | IEA | biological_process |
| GO:0046685 | response to arsenic-containing substance | IEA | biological_process |
| GO:0005615 | extracellular space | IDA | cellular_component |
| GO:0001501 | skeletal system development | TAS | biological_process |
| GO:0045779 | negative regulation of bone resorption | IEA | biological_process |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0043627 | response to estrogen stimulus | IEA | biological_process |
| GO:0005125 | cytokine activity | TAS | molecular_function |