Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TR10A_HUMAN
Description:tumor necrosis factor receptor superfamily, member 10a [Source:HGNC Symbol;Acc:11904]
Location:chr8 p21.3
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S463EDGTGsAVSHPRD; phosphoELM
S466TGSAVsLE___PhosphoSitePlus
S466TGSAVsHPRD; phosphoELM
S83PAREAsPRLRVPhosphoSitePlus; phosphoELM; SysPTM
Y456SGKFIyLEDGTPhosphoSitePlus
T461YLEDGtGSAVSPhosphoSitePlus; phosphoELM
S424TGRNAsIHTLLHPRD
S463EDGTGsAVSLEPhosphoSitePlus

Dephosphorylation site
TR10A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000221132C132FCOSMICOvarian Cancer21720365
ENSP00000221132K443NCOSMICCentral Nervous System Neoplasms18772890
ENSP00000221132R147QCOSMICOvarian Cancer21720365
ENSP00000221132A70TCOSMICCentral Nervous System Neoplasms18772890
ENSP00000221132P64SCOSMICCentral Nervous System Neoplasms18772890

Differential expressed protein
TR10A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TR10A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TNF10_HUMANTR10A_HUMANligand -> receptorHPMR
TNF10_HUMANTR10A_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04210Apoptosis
hsa05164Influenza A
hsa05162Measles
hsa04060Cytokine-cytokine receptor interaction
hsa04650Natural killer cell mediated cytotoxicity

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0007165signal transductionTASbiological_process
GO:0071260cellular response to mechanical stimulusIEPbiological_process
GO:0008134transcription factor bindingIPImolecular_function
GO:0004872receptor activityNASmolecular_function
GO:0045569TRAIL bindingNASmolecular_function
GO:0007250activation of NF-kappaB-inducing kinase activityNASbiological_process
GO:0097191extrinsic apoptotic signaling pathwayIDAbiological_process
GO:0016021integral to membraneICcellular_component
GO:0008625extrinsic apoptotic signaling pathway via death doNASbiological_process
GO:0006917induction of apoptosisNASbiological_process
GO:0005035death receptor activityTASmolecular_function
GO:0006919activation of cysteine-type endopeptidase activityNASbiological_process


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