| UniProt/SwissProt ID: | TNR21_HUMAN |
| Description: | tumor necrosis factor receptor superfamily, member 21 [Source:HGNC Symbol;Acc:13469] |
| Location: | chr6 p12.3 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S182 | SDVPSsVMKCK | GCC2_GCC3 | PhosphoSitePlus |
| Y648 | LLDSVySHLPD | CARD | PhosphoSitePlus |
| S564 | RCDSTsSGSSA | PhosphoSitePlus | |
| S571 | GSSALsRNGSF | PhosphoSitePlus | |
| S567 | STSSGsSALSR | PhosphoSitePlus | |
| S562 | LLRCDsTSSGS | PhosphoSitePlus | |
| S565 | CDSTSsGSSAL | PhosphoSitePlus | |
| S541 | LTVEPsPQDKN | PhosphoSitePlus; HPRD | |
| S568 | TSSGSsALSRN | PhosphoSitePlus | |
| S177 | ARGTFsDVPSS | GCC2_GCC3 | PhosphoSitePlus |
| S4 | __MGTsPSSST | PhosphoSitePlus | |
| T24 | RRATAtMIAGS | PhosphoSitePlus | |
| Y409 | REKWIyYCNGH | PhosphoSitePlus | |
| S13 | STALAsCSRIA | PhosphoSitePlus | |
| T563 | LRCDStSSGSS | PhosphoSitePlus | |
| S181 | FSDVPsSVMKC | GCC2_GCC3 | PhosphoSitePlus |
| S315 | LKLLPsMEATG | PhosphoSitePlus | |
| Y460 | DHERAyAALQH | Death | PhosphoSitePlus |
| Y434 | QWKDIyQFLCN | Death | PhosphoSitePlus |
| T22 | IARRAtATMIA | PhosphoSitePlus | |
| S649 | LDSVYsHLPDL | CARD | PhosphoSitePlus |
| T319 | PSMEAtGGEKS | PhosphoSitePlus | |
| T376 | RKSSRtLKKGP | DUF2078 | PhosphoSitePlus |
| Dephosphorylation site |
| TNR21_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000296861 | G320R | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| TNR21_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TNR21_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNFA_HUMAN | TNR21_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0051402 | neuron apoptotic process | IEA | biological_process |
| GO:0030424 | axon | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0044255 | cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0005886 | plasma membrane | TAS | cellular_component |