| UniProt/SwissProt ID: | TNR14_HUMAN |
| Description: | tumor necrosis factor receptor superfamily, member 14 [Source:HGNC Symbol;Acc:11912] |
| Location: | chr1 p36.32 |
| Node attribute: | receptor; PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y141 | AACRAyATSSP | HPRD | |
| Dephosphorylation site |
| TNR14_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000347948 | R243Q | COSMIC | Renal Cancer | 20054297 |
| Differential expressed protein |
| TNR14_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TNR14_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNF14_HUMAN | TNR14_HUMAN | ligand -> receptor | HPMR |
| TNFB_HUMAN | TNR14_HUMAN | other | KEGG |
| TNF14_HUMAN | TNR14_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa05168 | Herpes simplex infection |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0031625 | ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0009897 | external side of plasma membrane | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0031295 | T cell costimulation | TAS | biological_process |
| GO:0033209 | tumor necrosis factor-mediated signaling pathway | TAS | biological_process |
| GO:0050731 | positive regulation of peptidyl-tyrosine phosphory | IEA | biological_process |
| GO:0005031 | tumor necrosis factor-activated receptor activity | TAS | molecular_function |
| GO:0006955 | immune response | TAS | biological_process |
| GO:0019048 | virus-host interaction | IEA | biological_process |
| GO:0005887 | integral to plasma membrane | IC | cellular_component |
| GO:0007166 | cell surface receptor signaling pathway | TAS | biological_process |
| GO:0046642 | negative regulation of alpha-beta T cell prolifera | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |