| UniProt/SwissProt ID: | TNFL9_HUMAN |
| Description: | tumor necrosis factor (ligand) superfamily, member 9 [Source:HGNC Symbol;Acc:11939] |
| Location: | chr19 p13.3 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S158 | VAGEGsGSVSL | TNF | PhosphoSitePlus |
| S172 | LQPLRsAAGAA | TNF | PhosphoSitePlus |
| T182 | AALALtVDLPP | TNF | PhosphoSitePlus |
| S190 | LPPASsEARNS | TNF | PhosphoSitePlus |
| Dephosphorylation site |
| TNFL9_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000245817 | L124V | COSMIC | Ovarian Cancer | 21720365 | ENSP00000245817 | M1I | COSMIC | Skin Cancer | 21984974 |
| Differential expressed protein |
| TNFL9_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TNFL9_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TNFL9_HUMAN | TNR9_HUMAN | ligand -> receptor | HPMR |
| TNFL9_HUMAN | TNR9_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006955 | immune response | IEA | biological_process |
| GO:0006915 | apoptotic process | TAS | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0008283 | cell proliferation | TAS | biological_process |
| GO:0005125 | cytokine activity | IEA | molecular_function |
| GO:0005164 | tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005102 | receptor binding | TAS | molecular_function |
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0005102 | receptor binding | IEA | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0042127 | regulation of cell proliferation | IEA | biological_process |