| UniProt/SwissProt ID: | TN13B_HUMAN |
| Description: | tumor necrosis factor (ligand) superfamily, member 13b [Source:HGNC Symbol;Acc:11929] |
| Location: | chr13 q33.3 |
| Node attribute: | ligand; PPI(source) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S41 | SPSVRsSKDGK | PhosphoSitePlus | |
| Dephosphorylation site |
| TN13B_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000365048 | T228A | COSMIC | Skin Cancer | 21984974 | ENSP00000365048 | A88P | COSMIC | Ovarian Cancer | 21720365 | ENSP00000365048 | G137V | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| TN13B_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TN13B_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| TN13B_HUMAN | TR13C_HUMAN | ligand -> receptor | HPMR |
| TN13B_HUMAN | TR13B_HUMAN | ligand -> receptor | HPMR |
| TN13B_HUMAN | TNR17_HUMAN | other | KEGG |
| TN13B_HUMAN | TR13C_HUMAN | other | KEGG |
| TN13B_HUMAN | TR13B_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05323 | Rheumatoid arthritis |
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04672 | Intestinal immune network for IgA production |
| hsa04064 | NF-kappa B signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0031296 | B cell costimulation | IEA | biological_process |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0042102 | positive regulation of T cell proliferation | IEA | biological_process |
| GO:0008283 | cell proliferation | TAS | biological_process |
| GO:0031295 | T cell costimulation | IEA | biological_process |
| GO:0030890 | positive regulation of B cell proliferation | IEA | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0006955 | immune response | IEA | biological_process |
| GO:0050776 | regulation of immune response | IEA | biological_process |
| GO:0048305 | immunoglobulin secretion | IEA | biological_process |
| GO:0016021 | integral to membrane | NAS | cellular_component |
| GO:0005125 | cytokine activity | IEA | molecular_function |
| GO:0002636 | positive regulation of germinal center formation | IEA | biological_process |
| GO:0001782 | B cell homeostasis | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005164 | tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0005102 | receptor binding | TAS | molecular_function |
| GO:0008284 | positive regulation of cell proliferation | TAS | biological_process |