Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TF_HUMAN
Description:coagulation factor III (thromboplastin, tissue factor) [Source:HGNC Symbol;Acc:3541]
Location:chr1 p21.3
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S290SWKENsPLNHPRD; phosphoELM
S285AGVGQsWKENSHPRD; phosphoELM
S285AGVGQsWKENSstn_TNFRSF12A; Baculo_11_PhosphoSitePlus
S290SWKENsPLNVSBaculo_11_kDaPhosphoSitePlus
S290SWKENsPLNPKC_groupphosphoELM
S295SPLNVs_____PhosphoSitePlus
S285AGVGQsWKENSPKC_groupphosphoELM

Dephosphorylation site
TF_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000359226Y103SBIOMARTBreast Cancer21930507, 21930502
ENSP00000334145Y103SBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000359226Renal CancerNormal vs. CancertissueDown19164279

Hyperphosphorylation site
TF_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FA7_HUMANTF_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04610Complement and coagulation cascades

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051897positive regulation of protein kinase B signaling IMPbiological_process
GO:0031233intrinsic to external side of plasma membraneICcellular_component
GO:0045766positive regulation of angiogenesisIDAbiological_process
GO:0050927positive regulation of positive chemotaxisICbiological_process
GO:0002020protease bindingIPImolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0006919activation of cysteine-type endopeptidase activityIDAbiological_process
GO:0005543phospholipid bindingIDAmolecular_function
GO:0002543activation of blood coagulation via clotting cascaICbiological_process
GO:0043066negative regulation of apoptotic processTASbiological_process
GO:0043498cell surface bindingIDAmolecular_function
GO:0031012extracellular matrixIDAcellular_component
GO:0010641positive regulation of platelet-derived growth facIDAbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0007598blood coagulation, extrinsic pathwayTASbiological_process
GO:0001938positive regulation of endothelial cell proliferatIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0002541activation of plasma proteins involved in acute inIDAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0005886plasma membraneTAScellular_component
GO:0030335positive regulation of cell migrationTASbiological_process


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