Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TFPI1_HUMAN
Description:tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) [Source:HGNC Symbol;Acc:11760]
Location:chr2 q32.1
Node attribute:ligand; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S30PLNADsEEDEECK2_alphaphosphoELM
S30PLNADsEEDEEPhosphoSitePlus
S30PLNADsEEDEECK2a1(CK2 alphaRegPhos

Dephosphorylation site
TFPI1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000386344Y226*COSMICHead and Neck Cancer21798893
ENSP00000386344F240CCOSMICHead and Neck Cancer21798893

Differential expressed protein
TFPI1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TFPI1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TFPI1_HUMANVLDLR_HUMANligand -> receptorHPMR
CSK21_HUMANTFPI1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04610Complement and coagulation cascades

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005615extracellular spaceIDAcellular_component
GO:0010466negative regulation of peptidase activityIEAbiological_process
GO:0007598blood coagulation, extrinsic pathwayTASbiological_process
GO:0005783endoplasmic reticulumIEAcellular_component
GO:0031225anchored to membraneIEAcellular_component
GO:0010951negative regulation of endopeptidase activityTASbiological_process
GO:0004867serine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0030414peptidase inhibitor activityIEAmolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0004866endopeptidase inhibitor activityTASmolecular_function
GO:0031090organelle membraneIEAcellular_component
GO:0007596blood coagulationIEAbiological_process
GO:0005576extracellular regionIEAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23