Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TFF2_HUMAN
Description:trefoil factor 2 [Source:HGNC Symbol;Acc:11756]
Location:chr21 q22.3
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y93RRNCGyPGISPTrefoilPhosphoSitePlus

Dephosphorylation site
TFF2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000291526R4*COSMICPancreatic Cancer

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000291526hepatitis C virusNormal vs. Cancercell lineUp17928924

Hyperphosphorylation site
TFF2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GATA6_HUMANTFF2_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
TFF2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0070374positive regulation of ERK1 and ERK2 cascadeIEAbiological_process
GO:0007586digestionTASbiological_process
GO:0031723CXCR4 chemokine receptor bindingIEAmolecular_function
GO:0043031negative regulation of macrophage activationIEAbiological_process
GO:0070098chemokine-mediated signaling pathwayIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0050728negative regulation of inflammatory responseIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0060455negative regulation of gastric acid secretionIEAbiological_process
GO:0030334regulation of cell migrationIEAbiological_process
GO:0019722calcium-mediated signalingIEAbiological_process
GO:0008284positive regulation of cell proliferationIEAbiological_process


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