Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TESK1_HUMAN
Description:testis-specific kinase 1 [Source:HGNC Symbol;Acc:11731]
Location:chr9 p13.3
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S220LAVVGsPYWMATESK1HPRD; RegPhos
S441RSLPSsPELPRPhosphoSitePlus
S220LAVVGsPYWMAphosphoELM; RegPhos
S220LAVVGsPYWMAautocatalysis RegPhos
S553ERTEPsPPPSAPhosphoSitePlus
S437ARRCRsLPSSPPhosphoSitePlus
S69GAGFFsEVYKVPkinasePhosphoSitePlus

Dephosphorylation site
TESK1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000338127H539YSjoblom2006, HPI, BIOMART, Greenman2007Breast Cancer15908952, 16959974, 17344846, 18428421, 21930507, 21930502, 16959974, 17344846, 16959974 17344846
ENSP00000338127A160GTCGAOvarian Cancer21720365, 18772890
ENSP00000338127A252SBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
TESK1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TESK1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TESK1_HUMANTESK1_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANTESK1_HUMANkinase -> substrateRegPhos
TESK1_HUMANCOF1_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
TESK1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006468protein phosphorylationIEAbiological_process
GO:0004712protein serine/threonine/tyrosine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0004672protein kinase activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0007283spermatogenesisIEAbiological_process
GO:0034329cell junction assemblyTASbiological_process
GO:0005829cytosolTAScellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23