Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TAOK1_HUMAN
Description:TAO kinase 1 [Source:HGNC Symbol;Acc:29259]
Location:chr17 q11.2
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y309LDNLQyRKMKKPhosphoSitePlus
S987MSRSTsVTSQIPhosphoSitePlus
T185NSFVGtPYWMAPkinasePhosphoSitePlus
Y43SFGAVyFARDVPkinasePhosphoSitePlus
S66YSGKQsTEKWQPkinasePhosphoSitePlus
T669FRHLNtIQKMRPhosphoSitePlus
T734TCKIQtRQYKAPhosphoSitePlus
Y107WLVMEyCLGSAPkinasePhosphoSitePlus
S9TNRAGsLKDPEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S714RQQPKsLKSKEPhosphoSitePlus
S181ASPANsFVGTPPkinasePhosphoSitePlus
S421ASDPQsPPQVSPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S426SPPQVsRHKSHPhosphoSitePlus
S445TIRTAsLVTRQPhosphoSitePlus; HPRD; phosphoELM; SysPTM
T576NENQStPKKEKPhosphoSitePlus
S417PRTRAsDPQSPPhosphoSitePlus; HPRD; phosphoELM
Y406PEEENyREEGDPhosphoSitePlus
Y610RRQRQyLELECPhosphoSitePlus
T480QKQLMtLENKLPhosphoSitePlus
T643LNKRQtQKDLEPhosphoSitePlus
T440REHFAtIRTASPhosphoSitePlus
S965MGVRNsPQALRPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S959VPRGSsMGVRNHPRD; SysPTM
S958GVPRGsSMGVRHPRD; SysPTM
T1001SHMSYt_____PhosphoSitePlus
T785NEMLStQALRLPhosphoSitePlus
S554NSFLEsQKREYPhosphoSitePlus
T502DKDLEtQRNNFPhosphoSitePlus
Y432RHKSHyRNREHPhosphoSitePlus
S990STSVTsQISNGPhosphoSitePlus

Dephosphorylation site
TAOK1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000261716R860CCOSMICOvarian Cancer21720365
ENSP00000261716N639SBIOMARTNeoplasms by Histologic Type21930507, 21930502
ENSP00000261716E580KCOSMICMelanoma21499247
ENSP00000261716R606CCOSMICHead and Neck Cancer21798893

Differential expressed protein
TAOK1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
TAOK1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
TAOK1_HUMANMARK1_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04010MAPK signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0046330positive regulation of JNK cascadeIDAbiological_process
GO:0006281DNA repairIEAbiological_process
GO:0031572G2/M transition DNA damage checkpointIMPbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0016740transferase activityNASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0032874positive regulation of stress-activated MAPK cascaIMPbiological_process
GO:0000087M phase of mitotic cell cycleTASbiological_process
GO:0006974response to DNA damage stimulusIDAbiological_process
GO:0006468protein phosphorylationNASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0000278mitotic cell cycleTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0006915apoptotic processIDAbiological_process
GO:0000236mitotic prometaphaseTASbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0004674protein serine/threonine kinase activityISSmolecular_function
GO:0051493regulation of cytoskeleton organizationISSbiological_process
GO:0016301kinase activityNASmolecular_function
GO:0004672protein kinase activityIEAmolecular_function


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