| UniProt/SwissProt ID: | TAF5L_HUMAN |
| Description: | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa [Source:HGNC Symbol;Acc:17304] |
| Location: | chr1 q42.13 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S460 | AQQGNsVRLFT | WD40 | PhosphoSitePlus |
| S477 | LSLAFsPNGKY | WD40 | PhosphoSitePlus |
| T449 | GSTDKtVRLWS | WD40 | PhosphoSitePlus |
| Y422 | YPLRIyAGHLA | WD40 | PhosphoSitePlus |
| Y482 | SPNGKyLASAG | WD40 | PhosphoSitePlus |
| S25 | RQYVDsDGPLK | PhosphoSitePlus | |
| S454 | TVRLWsAQQGN | WD40 | PhosphoSitePlus |
| T443 | SNYLAtGSTDK | WD40 | PhosphoSitePlus |
| Dephosphorylation site |
| TAF5L_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000355636 | H307Q | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000258281 | H307Q | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000355635 | P254L | COSMIC | Ovarian Cancer | 21720365 | ENSP00000355635 | H307Q | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| TAF5L_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| TAF5L_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CSK21_HUMAN | TAF5L_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| TAF5L_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003713 | transcription coactivator activity | IDA | molecular_function |
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0043966 | histone H3 acetylation | IDA | biological_process |
| GO:0033276 | transcription factor TFTC complex | IDA | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | TAS | molecular_function |
| GO:0004402 | histone acetyltransferase activity | IDA | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0030914 | STAGA complex | IDA | cellular_component |