Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:TACD2_HUMAN
Description:tumor-associated calcium signal transducer 2 [Source:HGNC Symbol;Acc:11530]
Location:chr1 p32.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S303TNRRKsGKYKKPhosphoSitePlus
S322LRKEPHPRD; phosphoELM; SysPTM
S303TNRRKsGKYKKPKCa(PKC alphaRegPhos
S322LRKEPsL____PhosphoSitePlus; SysPTM
S322LRKEPsLRegPhos; SysPTM
S303TNRRKsGKYKKPKC_alphaphosphoELM

Dephosphorylation site
TACD2_HUMAN do not have dephosphorylation site.

Mutation site
TACD2_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000360269Oral CancerNormal vs. CancertissueDown0.319297561
ENSP00000360269Breast CancerTreatment (mitoxantrone-sensitive vs. mitoxantrone-resistant)cell lineDown0.2416335961
ENSP00000360269Breast CancerNormal vs. CancertissueDown0.4920739354

Hyperphosphorylation site
TACD2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANTACD2_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANTACD2_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
TACD2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0009925basal plasma membraneISScellular_component
GO:0090191negative regulation of branching involved in ureteIEAbiological_process
GO:0010633negative regulation of epithelial cell migrationIEAbiological_process
GO:0051497negative regulation of stress fiber assemblyIEAbiological_process
GO:0016328lateral plasma membraneISScellular_component
GO:0051497negative regulation of stress fiber assemblyISSbiological_process
GO:0016020membraneTAScellular_component
GO:0008283cell proliferationTASbiological_process
GO:0060675ureteric bud morphogenesisIEAbiological_process
GO:1900028negative regulation of ruffle assemblyISSbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0010633negative regulation of epithelial cell migrationISSbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0090191negative regulation of branching involved in ureteISSbiological_process
GO:0009925basal plasma membraneIEAcellular_component
GO:1900025negative regulation of substrate adhesion-dependenISSbiological_process
GO:0007601visual perceptionIEAbiological_process
GO:0004872receptor activityTASmolecular_function
GO:1900028negative regulation of ruffle assemblyIEAbiological_process
GO:0005829cytosolTAScellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0050678regulation of epithelial cell proliferationIEAbiological_process
GO:1900025negative regulation of substrate adhesion-dependenIEAbiological_process
GO:0016328lateral plasma membraneIEAcellular_component
GO:2000146negative regulation of cell motilityISSbiological_process
GO:2000146negative regulation of cell motilityIEAbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23