| UniProt/SwissProt ID: | SURF1_HUMAN |
| Description: | surfeit 1 [Source:HGNC Symbol;Acc:11474] |
| Location: | chr9 q34.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S52 | SAAEAsATKAE | PhosphoSitePlus | |
| Dephosphorylation site |
| SURF1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000361042 | Y274* | COSMIC | Ovarian Cancer | 21720365 | ENSP00000361042 | N89K | Sjoblom2006, COSMIC, HPI | Breast Cancer | 11317352, 16959974, 18428421, 11317352, 16959974, 11317352 16959974 |
| Differential expressed protein |
| SURF1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SURF1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ETS2_HUMAN | SURF1_HUMAN | TF -> target gene | TRANSFAC |
| TYY1_HUMAN | SURF1_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| SURF1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0055114 | oxidation-reduction process | TAS | biological_process |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0008535 | respiratory chain complex IV assembly | TAS | biological_process |
| GO:0006119 | oxidative phosphorylation | IMP | biological_process |
| GO:0005746 | mitochondrial respiratory chain | TAS | cellular_component |
| GO:0004129 | cytochrome-c oxidase activity | IEA | molecular_function |
| GO:0005739 | mitochondrion | IEA | cellular_component |
| GO:0006754 | ATP biosynthetic process | IMP | biological_process |
| GO:0009060 | aerobic respiration | TAS | biological_process |