| UniProt/SwissProt ID: | STON1_HUMAN |
| Description: | stonin 1 [Source:HGNC Symbol;Acc:17003] |
| Location: | chr2 p16.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S404 | KLPAVsKPKKN | Adap_comp_sub | PhosphoSitePlus |
| S225 | SLNKCsLNYIC | PhosphoSitePlus | |
| Y628 | KYESAyQAVVW | Adap_comp_sub | PhosphoSitePlus |
| T346 | AGKIHtVKIEH | PhosphoSitePlus | |
| S209 | KKMFSsRNKEM | PhosphoSitePlus | |
| Dephosphorylation site |
| STON1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000310969 | P28S | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| STON1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| STON1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| UHMK1_HUMAN | STON1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK4_HUMAN | STON1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ST17A_HUMAN | STON1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| STON1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0030100 | regulation of endocytosis | IDA | biological_process |
| GO:0016192 | vesicle-mediated transport | IEA | biological_process |
| GO:0006886 | intracellular protein transport | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0006897 | endocytosis | IEA | biological_process |
| GO:0030131 | clathrin adaptor complex | IEA | cellular_component |