Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SSRP1_HUMAN
Description:structure specific recognition protein 1 [Source:HGNC Symbol;Acc:11327]
Location:chr11 q12.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S659RQLSEsFKSKEPhosphoSitePlus; HPRD; phosphoELM
Y614KAMKEyEGGRGHMG_boxPhosphoSitePlus
S678SGENKsKKKRRPhosphoSitePlus
S315LYEMVsRVMKAPhosphoSitePlus
S510SNEGDsDRDEKCK2a1-rsRegPhos
S510SNEGDsDRDEKCK2_groupRegPhos
S688RRSEDsEEEELCSNK2A1HPRD
S510SNEGDsDRDEKCK2a1RegPhos
S307LTKNMsGSLYEHPRD
S258MFFVIsLDPPISSrecogPhosphoSitePlus
T170FYVPPtQEDGVHPRD; phosphoELM
S652SSSKSsSRQLSPhosphoSitePlus
S278LILLFsKDEDISSrecogPhosphoSitePlus
S662SESFKsKEFVSPhosphoSitePlus; HPRD
Y270QGQTRyHFLILSSrecogPhosphoSitePlus
S621GGRGEsSKRDKHPRD
Y270QGQTRyHFLILHPRD
S578SITDLsKKAGEHPRD
S688RRSEDsEEEELPhosphoSitePlus
S444DEYADsDEDQHPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S688RRSEDsEEEELCK2_alphaphosphoELM
S644KKSTPsRGSSSPhosphoSitePlus; HPRD
S673SDESSsGENKSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S668KEFVSsDESSSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S657SSRQLsESFKSCSNK2A1HPRD
S647TPSRGsSSKSSHPRD
Y452DQHDAyLERMKPhosphoSitePlus; HPRD
Y441PSYDEyADSDEPhosphoSitePlus; HPRD; RegPhos
S688RRSEDsEEEELCK2a1-rsRegPhos
Y311MSGSLyEMVSRPhosphoSitePlus; HPRD; RegPhos
S657SSRQLsESFKSPhosphoSitePlus; phosphoELM; RegPhos
S17QEVKGsMNDGRPhosphoSitePlus; HPRD
S567REKIKsDHPGIHPRD
S258MFFVIsLDPPIHPRD
S641KMEKKsTPSRGPhosphoSitePlus; HPRD
S671VSSDEsSSGENPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S309KNMSGsLYEMVPhosphoSitePlus; HPRD
S657SSRQLsESFKSCK2a1-rsRegPhos
S510SNEGDsDRDEKPhosphoSitePlus
T170FYVPPtQEDGVSSrecogPhosphoSitePlus
S688RRSEDsEEEELCK2a1RegPhos
S510SNEGDsDRDEKCSNK2A1HPRD
S510SNEGDsDRDEKCK2a1(CK2 alphaRegPhos
S561LWLNAsREKIKHPRD; phosphoELM; RegPhos
Y438GMNPSyDEYADPhosphoSitePlus; HPRD; phosphoELM
S657SSRQLsESFKSCK2a1RegPhos
S649SRGSSsKSSSRHPRD
S688RRSEDsEEEELCK2_groupRegPhos
S688RRSEDsEEEELCK2a1(CK2 alphaRegPhos
S667SKEFVsSDESSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T642MEKKStPSRGSHPRD
S510SNEGDsDRDEKCK2_alphaphosphoELM
S437EGMNPsYDEYAPhosphoSitePlus; HPRD; phosphoELM
S672SSDESsSGENKPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T696EELAStPPSSEPhosphoSitePlus
Y554RPMSAyMLWLNHPRD; phosphoELM; RegPhos
S578SITDLsKKAGEHMG_boxPhosphoSitePlus
S278LILLFsKDEDIHPRD

Dephosphorylation site
SSRP1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000278412T575MCOSMICOvarian Cancer21720365

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000278412Hepatocellular CarcinomaNormal vs. Cancercell lineDown0.3618646787
ENSP00000278412Hepatocellular CarcinomaNormal vs. Cancercell lineDown0.4418646787
ENSP00000278412Gastric CancerMetastasiscell lineDown0.6817022644
ENSP00000278412Gastric CancerMetastasiscell lineDown0.6817022644

Hyperphosphorylation site
SSRP1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK21_HUMANSSRP1_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
ZAGL2_HUMANSSRP1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
SSRP1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006368transcription elongation from RNA polymerase II prTASbiological_process
GO:0005634nucleusIDAcellular_component
GO:0003682chromatin bindingIEAmolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005694chromosomeIEAcellular_component
GO:0005654nucleoplasmTAScellular_component
GO:0006260DNA replicationIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0016032viral reproductionTASbiological_process
GO:0050434positive regulation of viral transcriptionTASbiological_process
GO:0006281DNA repairIEAbiological_process
GO:0010467gene expressionTASbiological_process
GO:0005730nucleolusIEAcellular_component
GO:0005515protein bindingIPImolecular_function