Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SP4_HUMAN
Description:Sp4 transcription factor [Source:HGNC Symbol;Acc:11209]
Location:chr7 p15.3
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S126ASSSSsSSSSNPhosphoSitePlus
T138GSASPtKTKSGPhosphoSitePlus; HPRD; phosphoELM
T20AAAMAtEGGKTPhosphoSitePlus
T700QRHRRtHTGEKzf-C2H2PhosphoSitePlus
S130SSSSSsNNGSAPhosphoSitePlus
S125PASSSsSSSSSPhosphoSitePlus
S127SSSSSsSSSNNPhosphoSitePlus
T774DSNPAtPNVSTPhosphoSitePlus
S767TVAAIsQDSNPHPRD
S691KRFTRsDELQRzf-C2H2PhosphoSitePlus; SysPTM
S136NNGSAsPTKTKPhosphoSitePlus; HPRD
S770AISQDsNPATPPhosphoSitePlus
S691KRFTRsDELQRHPRD; phosphoELM; SysPTM
T672HLRWHtGERPFPhosphoSitePlus
S124QPASSsSSSSSPhosphoSitePlus
T702HRRTHtGEKRFPhosphoSitePlus

Dephosphorylation site
SP4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000222584D388ECOSMICOvarian Cancer21720365
ENSP00000222584R665*COSMICOvarian Cancer21720365
ENSP00000222584R665*TCGAOvarian Cancer21720365, 18772890
ENSP00000222584I648VCOSMICHead and Neck Cancer21798893
ENSP00000222584P628LCOSMICMelanoma21499247
ENSP00000222584Q415ECOSMICOvarian Cancer21720365
ENSP00000222584Q415ETCGAOvarian Cancer21720365, 18772890
ENSP00000222584D388ETCGAOvarian Cancer21720365, 18772890

Differential expressed protein
SP4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SP4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SP4_HUMANHAND1_HUMANTF -> target geneTRANSFAC
SP4_HUMANCCND1_HUMANTF -> target geneTRANSFAC
SP4_HUMANPHX2A_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
SP4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008270zinc ion bindingIEAmolecular_function
GO:0003713transcription coactivator activityTASmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0006357regulation of transcription from RNA polymerase IIIDAbiological_process


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