Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SNP25_HUMAN
Description:synaptosomal-associated protein, 25kDa [Source:HGNC Symbol;Acc:11132]
Location:chr20 p12.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S187MEKADsNKTRIExonuc_VII_L; SNAREPhosphoSitePlus
S187MEKADsNKTRIPRKCAHPRD
T138FIRRVtNDAREPRKCAHPRD
T138FIRRVtNDAREPKCaRegPhos
T29ESLEStRRMLQIncA; Sec34; Exonuc_VII_LPhosphoSitePlus
S187MEKADsNKTRIPKCaRegPhos
S187MEKADsNKTRIRegPhos
T138FIRRVtNDARERegPhos
S28DESLEsTRRMLIncA; Sec34; Exonuc_VII_LPhosphoSitePlus
T138FIRRVtNDAREPRKACAHPRD
T138FIRRVtNDAREExonuc_VII_L; SNAP-25PhosphoSitePlus
T138FIRRVtNDAREPKACaRegPhos

Dephosphorylation site
SNP25_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000307341R59CCOSMICMelanoma21499247
ENSP00000307341Q56*COSMICHead and Neck Cancer21798893

Differential expressed protein
SNP25_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SNP25_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KPCA_HUMANSNP25_HUMANkinase -> substrateHPRD
ZAGL2_HUMANSNP25_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04721Synaptic vesicle cycle
hsa04130SNARE interactions in vesicular transport

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045202synapseIEAcellular_component
GO:0007268synaptic transmissionNASbiological_process
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0016020membraneIEAcellular_component
GO:0031083BLOC-1 complexIDAcellular_component
GO:0031201SNARE complexISScellular_component
GO:0005802trans-Golgi networkIEAcellular_component
GO:0030054cell junctionIEAcellular_component
GO:0006112energy reserve metabolic processTASbiological_process
GO:0050796regulation of insulin secretionTASbiological_process
GO:0014047glutamate secretionTASbiological_process
GO:0005737cytoplasmISScellular_component
GO:0005515protein bindingIPImolecular_function
GO:0007269neurotransmitter secretionIEAbiological_process
GO:0000149SNARE bindingIEAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0070032synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I coIEAcellular_component
GO:0001504neurotransmitter uptakeNASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0030426growth coneISScellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0016020membraneISScellular_component
GO:0016192vesicle-mediated transportIEAbiological_process
GO:0043005neuron projectionISScellular_component
GO:0016081synaptic vesicle docking involved in exocytosisNASbiological_process
GO:0007269neurotransmitter secretionNASbiological_process
GO:0005737cytoplasmIEAcellular_component


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