Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SMAL1_HUMAN
Description:SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 [Source:HGNC Symbol;Acc:11102]
Location:chr2 q35
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S952WDSFTsPL___PhosphoSitePlus
S533SFDLLsKLEKQSNF2_NPhosphoSitePlus
S528LINIVsFDLLSSNF2_NPhosphoSitePlus
Y872TESTDyLYKDPPhosphoSitePlus
S198KTAKAsPSGQNHPRD; phosphoELM
T867NFSEMtESTDYHPRD
S627WDYSGsSNLGESNF2_NPhosphoSitePlus
T157PEIRFtPFANPPhosphoSitePlus
Y306PLEWAyGSSESPhosphoSitePlus
S172LAKPKsSQETPPhosphoSitePlus
S112ACPGHsPRSQMPhosphoSitePlus
S151GHAQAsPEIRFPhosphoSitePlus; HPRD
Y874STDYLyKDPKQPhosphoSitePlus
S211YIHSSsESVTPPhosphoSitePlus
S181TPAHSsGQPPRPhosphoSitePlus
S652KSDVLsQLPAKSNF2_NPhosphoSitePlus
T215SSESVtPRTEGPhosphoSitePlus

Dephosphorylation site
SMAL1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000349823P199RTCGAOvarian Cancer21720365, 18772890
ENSP00000350940A355VCOSMICMelanoma
ENSP00000350940P199RCOSMICOvarian Cancer21720365
ENSP00000350940L432VSjoblom2006, COSMIC, HPIBreast Cancer16959974, 18428421
ENSP00000349823A355VCOSMICMelanoma
ENSP00000349823F886LBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000349823L432VSjoblom2006, COSMIC, HPIBreast Cancer16959974, 18428421
ENSP00000349823P199RCOSMICOvarian Cancer21720365
ENSP00000350940P199RTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
SMAL1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SMAL1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEK3_HUMANSMAL1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SMAL1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008094DNA-dependent ATPase activityIEAmolecular_function
GO:0016568chromatin modificationIEAbiological_process
GO:0006357regulation of transcription from RNA polymerase IIIMPbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0000733DNA strand renaturationIMPbiological_process
GO:0036310annealing helicase activityIMPmolecular_function
GO:0006259DNA metabolic processIMPbiological_process
GO:0004386helicase activityIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005524ATP bindingIEAmolecular_function


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