| UniProt/SwissProt ID: | SH22A_HUMAN |
| Description: | SH2 domain containing 2A [Source:HGNC Symbol;Acc:10821] |
| Location: | chr1 q23.1 |
| Node attribute: | PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y290 | EPIAFyAMGRG | PhosphoSitePlus; HPRD; phosphoELM | |
| Y260 | LPPEVyTIPVP | PhosphoSitePlus | |
| S43 | GYTAAsPQAPE | PhosphoSitePlus | |
| Y216 | DPNPQySPIIK | PhosphoSitePlus; HPRD; phosphoELM | |
| Y178 | HPLSPyGETLT | PhosphoSitePlus | |
| Y305 | APSNIyVEVED | PhosphoSitePlus; HPRD; phosphoELM | |
| S371 | LPHNLsRQVLQ | PhosphoSitePlus | |
| Y39 | CQNLGyTAASP | PhosphoSitePlus; phosphoELM | |
| S302 | PGEAPsNIYVE | PhosphoSitePlus | |
| T261 | PPEVYtIPVPR | PhosphoSitePlus | |
| S296 | AMGRGsPGEAP | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Y280 | PSNPIyNEPDE | PhosphoSitePlus; HPRD; phosphoELM | |
| S217 | PNPQYsPIIKQ | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Dephosphorylation site |
| SH22A_HUMAN do not have dephosphorylation site. |
| Mutation site |
| SH22A_HUMAN do not have mutation site. |
| Differential expressed protein |
| SH22A_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SH22A_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ACM1_HUMAN | SH22A_HUMAN | other | KEGG |
| VGFR2_HUMAN | SH22A_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04370 | VEGF signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0030154 | cell differentiation | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0001525 | angiogenesis | IEA | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0008283 | cell proliferation | IEA | biological_process |