Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SESN1_HUMAN
Description:sestrin 1 [Source:HGNC Symbol;Acc:21595]
Location:chr6 q21
Node attribute:gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S314MFVFSsDDEEVPA26PhosphoSitePlus
S293DEEEAsQEEMAPA26PhosphoSitePlus
S352DEEEAsQEEMAHPRD
S293DEEEAsQEEMAphosphoELM

Dephosphorylation site
SESN1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000393762G104RCOSMICOvarian Cancer21720365

Differential expressed protein
SESN1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SESN1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
P53_HUMANSESN1_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
SESN1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008285negative regulation of cell proliferationTASbiological_process
GO:0006974response to DNA damage stimulusTASbiological_process
GO:0007050cell cycle arrestIEAbiological_process
GO:0005634nucleusIEAcellular_component


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